OASB02739 | Type I Collagen Antibody : FITC Clinisciences

Type I Collagen Antibody : FITC (OASB02739)

Datasheets/Manuals	Printable datasheet for Type I Collagen Antibody : FITC (OASB02739)

Product Info
Tested Species Reactivity	Human
Predicted Species Reactivity	Mouse, Rat, Bovine, Canine, Chicken, Chinchilla, Elephant, Feline, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Tree Shrew
Product Format	Liquid PBS/sodium azide
Clonality	Polyclonal
Host	Goat
Conjugation	FITC
Application	FC, FLISA, ICC, IHC-F, IHC-P, WB
Reconstitution and Storage	Store at 2-8°C
Purification	Affinity chromatography on type I collagen covalently linked to agarose.
Concentration	Varies by lot. See vial for concentration.
Specificity	Reacts with conformational determinants on type I collagen. Cross adsorption with collagen types II, III, IV, V, and VI
Application Info	FLISA: 1:200 - 1:400

Gene Symbol	COL1A1, COL1A2
Gene Full Name	collagen type I alpha 1 chain
Alias Symbols	OI1, OI2, OI3, OI4, EDSC, CAFYD, EDSARTH1
NCBI Gene Id	1277; 1278
Protein Name	collagen alpha-1(I) chain
Description of Target	This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Uniprot ID	P02452, P08123
Protein Accession #	NP_000079.2
Nucleotide Accession #	NM_000088.3