Virus-Like Particle (VLP) Protein Isotype Control

Katalog-Nummer C40D-100ug

Size : 100ug

Marke : Novoprotein


Description
VLPs are self-assembled from viral envelope/capsid protein and can display conformationally intact membrane protein in natural cell membranes.
Known As
VLP; Virus Like Particle; eVLP; VLPs
Formulation Description
Supplied as a 0.2 μm filtered solution of PBS, 30% Trehalose, pH 7.4.
Endotoxin
< 1 EU/µg as determined by LAL test.
Purity-SEC-HPLC
Greater than 90% as determined by SEC-HPLC.(QC verified)
Shipping
  • The product is shipped on dry ice/polar packs.
  • Upon receipt, store it immediately at the temperature listed below.
Storage
  • Store at ≤-70°C, stable for 12 months under sterile conditions.
  • Please minimize freeze-thaw cycles.
Background
Virus-like particles (VLPs) are virus-derived structures made up of one or more different molecules with the ability to self-assemble, mimicking the form and size of a virus particle but lacking the genetic material so they are not capable of infecting the host cell. Expression and self-assembly of the viral structural proteins can take place in various living or cell-free expression systems after which the viral structures can be assembled and reconstructed. VLPs are gaining in popularity in the field of preventive medicine and to date, a wide range of VLP-based candidate vaccines have been developed for immunization against various infectious agents, the efficacy of which is being evaluated. VLPs are highly immunogenic and are able to elicit both the antibody- and cell-mediated immune responses by pathways different from those elicited by conventional inactivated viral vaccines.