Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Hybridization position of the probes on the chromosome.
Hybridization position of the probes on the chromosome.
- Specifications
Probe 1
Name: TGFBR3
Size: Approximately 420kb
Fluorophore: Texas Red
Location: 1ｐ22.1Probe 2
Name: TGFBR3
Size: Approximately 590kb
Fluorophore: FITC
Location: 1ｐ22.1Regulation Status
For research use only (RUO)
Source
Genomic DNA
Origin
Human
Notice
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
Self-Attestation
Abnova self-attests to comply with the U.S. Framework for Nucleic Acid Synthesis Screening
Product Description
Labeled FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. ().
Reactivity
Human
Form
Liquid
Quality Control Testing
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Storage Instruction
Store at 4°C in the dark.
Note
Hybridization position of the probes on the chromosome. - Applications
Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Fluorescent In Situ Hybridization (Cell)
- Gene Info — RUNX1
Entrez GeneID
861Gene Name
RUNX1
Gene Alias
AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Gene Description
runt-related transcription factor 1
Gene Ontology
HyperlinkGene Summary
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
AML1-EVI-1 fusion protein|acute myeloid leukemia 1|aml1 oncogene|core-binding factor, runt domain, alpha subunit 2
- Interactomes
- Pathways
- Diseases