Bobcat339 [2280037-51-4]

Katalog-Nummer orb1302003-10mg

Size : 10mg

Marke : Biorbyt


Bobcat339

SKU: orb1302003

Description

Bobcat339

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number2280037-51-4
MW297.74
Purity98.76% (May vary between batches)
FormulaC16H12ClN3O
SMILESNc1nc(=O)n(cc1Cl)-c1cccc(c1)-c1ccccc1
TargetDNA Methyltransferase
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.72 mM);DMSO:11.59 mg/mL (38.93 mM)

Bioactivity

Target IC50
TET2:73 μM (cell free)|TET1:33 μM (cell free)
In Vitro
HT-22 cells were treated with 10 μM Bobcat339 in 1% DMSO for 24 hrs and lysed. Cells treated with Bobcat339 had significantly reduced global 5hmC levels as compared to vehicle control.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TET1, TET2, epigenetics, DNA Methyltransferase, DNA methyltransferase (DNMT), DNA MTases, DNAMethyltransferase, DNMTs, Cytosine-based,TET, Bobcat 339, Bobcat339, Bobcat339, Bobcat-339, Bobcat339 hydrochloride, Bobcat339 hydrochloride
  • Bobcat339 hydrochloride [orb1689025]

    2436747-44-1

    334.2

    C16H13Cl2N3O

    100 mg, 5 mg, 2 mg, 1 ml x 10 mM (in DMSO), 25 mg, 10 mg, 50 mg, 200 mg
  • Bobcat339 [orb1225600]

    >98% (HPLC)

    2280037-51-4

    297.742

    C16H12ClN3O

    5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g, 25 mg

Key Properties

No computed properties available.

Protocol Information