Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie

Citronellol [106-22-9]

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Katalog-Nummer NB-64-20779-2g

Size : 2g

Marke : Neo Biotech

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Citronellol (Synonyms: dihydrogeraniol)

Catalog No. T3240 Copy Product Info

Purity: 99.56%

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Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.

Citronellol

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Synonyms dihydrogeraniol

Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.

Cas No. 106-22-9

Batch Information

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Purity:99.56%

Appearance:Liquid

Color:Transparent

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COA HNMR

Product Introduction

Citronellol AI Summary

Citronellol demonstrates a diverse range of biological activities and inhibitory effects against various targets. It has antiplasmodial activity with an IC50 of 192,000.0 nM against chloroquine-resistant Plasmodium falciparum FcM29-Cameroon but does not exhibit significant antifungal activity against Candida albicans ATCC 90028 (MIC > 200.0 ug/mL). The compound shows inhibition of COX2 by less than 30.0% at 100 uM and is identified as a potential inhibitor of Aldehyde Dehydrogenase 1 (ALDH1A1) with a potency of 3548.1 nM. It also inhibits 15-human lipoxygenase (15-hLO) with a potency of 7943.3 nM and modulates lipid storage with a potency of 39810.7 nM. Additionally, it exhibits agonistic activity toward the antioxidant response element (ARE) signaling pathway with a potency of 74978.0 nM and is a potential inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1) with a potency of 32642.7 nM. Citronellol is characterized by specific activity against human recombinant UGT1A1, demonstrating 0.0 pm/min/mg activity. It shows strong repellent activity against Tribolium castaneum and insecticidal activity against Leptinotarsa decemlineata and two-spotted spider mites, including insecticidal efficacy against both susceptible and resistant strains. The compound exhibits fungitoxicity against Colletotrichum gloeosporioides (EC50 = 84.0 ug/mL and 537031.8 nM) and antimicrobial activity against Mycobacterium tuberculosis H37Rv, with complete growth inhibition at 64.0 ug/mL. Additionally, Citronellol exhibits mixed activities on transient receptor potential (TRP) channels, with varying levels of agonist and antagonist effects on TRPV1, TRPA1, and TRPM8. It also shows inhibitory activity against ARAT in bovine RPE microsomes (30% inhibition at 100 uM) and no inhibitory activity towards LRAT under similar conditions. The compound has a logP value of 3.91, indicating moderate lipophilicity, and displays varied bioactivities against multiple microbial and insect targets..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.
Synonyms	dihydrogeraniol

Chemical Properties

Molecular Weight	156.27
Formula	C₁₀H₂₀O
Cas No.	106-22-9
Smiles	C(CCC=C(C)C)(CCO)C
Relative Density.	0.857 g/cm3 at 25℃ (lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (319.96 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (12.8 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.3992 mL	31.9959 mL	63.9918 mL	319.9590 mL
5 mM	1.2798 mL	6.3992 mL	12.7984 mL	63.9918 mL
10 mM	0.6399 mL	3.1996 mL	6.3992 mL	31.9959 mL
20 mM	0.3200 mL	1.5998 mL	3.1996 mL	15.9980 mL
50 mM	0.1280 mL	0.6399 mL	1.2798 mL	6.3992 mL
100 mM	0.0640 mL	0.3200 mL	0.6399 mL	3.1996 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.