Orb216573-10mg | Endothelin 1 Human peptide Clinisciences

Endothelin 1 Human peptide

SKU: orb216573

Description

Endothelin 1 Human peptide

Images & Validation

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Application Notes	Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.

Application Notes

Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.

Key Properties

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Source	Synthetic
CAS Number	117399-94-7
MW	2491.95
Purity	> 95%
Formula	C₁₀₉H₁₅₉N₂₅O₃₂S₅
Protein Sequence	H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bridge Cys1-Cys15, Cys3-Cys11)

Storage & Handling

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Storage	Shipped at 4°C. Store at -20°C for one year.
Form/Appearance	Lyophilized powder
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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ET-1 (human, bovine, dog, mouse, porcine, rat)

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Endothelin 1 Rabbit Polyclonal Antibody [orb13403]
Applications:
ELISA, ICC, IF, WB
Reactivity:
Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat, Sheep
Species/Host:
Rabbit
Clonality:
Polyclonal
Conjugation:
Unconjugated
Sizes Available: 100 μg
ETAR rabbit pAb Antibody [orb765180]
Applications:
ELISA, IF, IHC, WB
Reactivity:
Human, Monkey, Mouse
Clonality:
Polyclonal
Conjugation:
Unconjugated
Sizes Available: 50 μl, 100 μl
GPR37L1 rabbit pAb Antibody [orb770885]
Applications:
ELISA, IF, IHC, WB
Reactivity:
Human, Mouse, Rat
Clonality:
Polyclonal
Conjugation:
Unconjugated
Sizes Available: 50 μl, 100 μl
GPR37 Antibody [orb687084]
Applications:
ELISA, IF, IHC, WB
Reactivity:
Human
Species/Host:
Rabbit
Clonality:
Polyclonal
Conjugation:
Unconjugated
Sizes Available: 100 μl, 50 μl
Endothelin A Receptor Rabbit Polyclonal Antibody [orb213870]
Applications:
IF, IHC, WB
Reactivity:
Human
Species/Host:
Rabbit
Clonality:
Polyclonal
Conjugation:
Unconjugated
Sizes Available: 30 μl, 100 μl, 200 μl, 50 μl

Protocol Information

Protein Handling and Storage Guide

Protein Handling Guide

View Guide

Endothelin 1 Human peptide

Katalog-Nummer orb216573-10mg

Marke : Biorbyt

Endothelin 1 Human peptide

Description

Images & Validation

Key Properties

Storage & Handling

Alternative Names

Endothelin 1 Rabbit Polyclonal Antibody [orb13403]

ETAR rabbit pAb Antibody [orb765180]

GPR37L1 rabbit pAb Antibody [orb770885]

GPR37 Antibody [orb687084]

Endothelin A Receptor Rabbit Polyclonal Antibody [orb213870]

Protocol Information

Applications:	ELISA, ICC, IF, WB
Reactivity:	Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat, Sheep
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Applications:	ELISA, IF, IHC, WB
Reactivity:	Human, Monkey, Mouse
Clonality:	Polyclonal
Conjugation:	Unconjugated

Applications:	IF, IHC, WB
Reactivity:	Human
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated