fbpC

Katalog-Nummer 562388-50ug

Size : 50ug

Marke : US Biological



562388 fbpC

Clone Type
Polyclonal
Host
rabbit
Source
Mycobacterium tuberculosis
Swiss Prot
P9WQN8
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Shipping Temp
Blue Ice
Storage Temp
-20°C

The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:5000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: Mycobacterium tuberculosis|Concentration: As Reported |Form: Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.|Purity: Purified by Protein G affinity chromatography.|Immunogen: Recombinant protein corresponding to aa46-340 from mycobacterium tuberculosis diacylglycerol acyltransferase/mycolyltransferase Ag85C protein.|Specificity: Recognizes mycobacterium tuberculosis fbpC.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant protein corresponding to aa46-340 from mycobacterium tuberculosis diacylglycerol acyltransferase/mycolyltransferase Ag85C protein.
Form
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes mycobacterium tuberculosis fbpC.