inhA Recombinant Protein
Katalog-Nummer OPCA02159-1MG
Size : 1mg
Marke : Aviva Systems Biology
INHA Recombinant Protein (Mycobacterium tuberculosis) (OPCA02159)
| Datasheets/Manuals | Printable datasheet for INHA Recombinant Protein (Mycobacterium tuberculosis) (OPCA02159) |
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| Predicted Species Reactivity | Mycobacterium tuberculosis |
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| Product Format | Liquid or Lyophilized powder |
| Host | Mycobacterium tuberculosis |
| Reconstitution and Storage | -20°C or -80°C |
| Formulation | 20 mM Tris-HCl based buffer, pH 8.0 |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Peptide Sequence | MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL |
| Protein Sequence | MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL |
| Storage Buffer | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| Source | E.coli |
| Protein Range | 1-269 aa |
| Tag | N-terminal 6xHis-SUMO-tagged |
| Reference | Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis.He X., Alian A., Stroud R., Ortiz de Montellano P.R.J. Med. Chem. 49:6308-6323(2006) |
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| Gene Symbol | INHA |
| Alias Symbols | FAS-II enoyl-ACP reductase, NADH-dependent 2-trans-enoyl-ACP reductase. |
| Protein Name | Enoyl-[acyl-carrier-protein] reductase [NADH] |
| Description of Target | Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system, which is involved in the biosynthesis of mycolic acids, a major component of mycobacterial cell walls. Catalyzes the NADH-dependent reduction of the double bond of 2-trans-enoyl-[acyl-carrier protein], an essential step in the fatty acid elongation cycle of the FAS-II pathway. Shows preference for long-chain fatty acyl thioester substrates (>C16), and can also use 2-trans-enoyl-CoAs as alternative substrates. The mycobacterial FAS-II system utilizes the products of the FAS-I system as primers to extend fatty acyl chain lengths up to C56, forming the meromycolate chain that serves as the precursor for final mycolic acids. |
| Uniprot ID | P9WGR0 |
| Protein Size (# AA) | Full Length |
| Molecular Weight | 44.5 kda |
