CD54 FITC
Catalog #
Size
Daudi cell line stained with CD54 FITC (RED); Daudi cell line stained with mouse IgG2b FITC (BLUE).
| Conjugation | FITC |
|---|---|
| Antigen | CD54 |
| Clone | LB-2 |
| Isotype | IgG2b, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
| Excitation Laser | Blue (488nm) |
Description:
The clone LB-2 specifically binds with CD54 also known as Intercellular adhesion molecule-1 (ICAM-1), a cell surface antigen expressed by various types of human immune and non-immune cells. CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the Ig supergene family and is a surrogate marker of antigen presenting cell activation. CD54 is expressed mostly on endothelial cells. It also weakly expressed by naïve B and T cells and moderately expressed on activated B and T cells as well as monocytes. CD54 is highly expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, and B-lymphoblastoid cells. The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia.
The clone LB-2 specifically binds with CD54 also known as Intercellular adhesion molecule-1 (ICAM-1), a cell surface antigen expressed by various types of human immune and non-immune cells. CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the Ig supergene family and is a surrogate marker of antigen presenting cell activation. CD54 is expressed mostly on endothelial cells. It also weakly expressed by naïve B and T cells and moderately expressed on activated B and T cells as well as monocytes. CD54 is highly expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, and B-lymphoblastoid cells. The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia.