SAG 21k [946002-48-8]

Katalog-Nummer T35559-50mg

Size : 50mg

Marke : TargetMol


SAG 21k

Copy Product Info
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
SAG 21k
Cas No. 946002-48-8
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.95%
Appearance:Solid
Color:Yellow
COA LCMS HNMR

Product Information

Bioactivity
Description
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
Chemical Properties
Molecular Weight556.07
FormulaC29H28ClF2N3O2S
Cas No.946002-48-8
SmilesClC=1C=2C(SC1C(N(CC3=C(OC)C=CC(=C3)C=4C=CN=CC4)[C@H]5CC[C@H](NC)CC5)=O)=C(F)C=CC2F
Storage & Solubility Information
StorageStore at low temperature,Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (89.92 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Saline: < 5 mg/mL (8.99 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (8.99 mM), Solution.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7983 mL8.9917 mL17.9833 mL89.9167 mL
5 mM0.3597 mL1.7983 mL3.5967 mL17.9833 mL
10 mM0.1798 mL0.8992 mL1.7983 mL8.9917 mL
20 mM0.0899 mL0.4496 mL0.8992 mL4.4958 mL
50 mM0.0360 mL0.1798 mL0.3597 mL1.7983 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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