Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> TEAD4 Protein, Mouse, Recombinant

TEAD4 Protein, Mouse, Recombinant

Drucken Drucken
Melden Sie sich an

Katalog-Nummer NB-64-51612-100ug

Size : 100ug

Marke : Neo Biotech


Remove All

TEAD4 Protein, Mouse, Recombinant

(Synonyms: Transcriptional enhancer factor TEF-3, Tefr1, Tef3, TEF-1-related factor FR-19 (RTEF-1), TEF-1-related factor 1, Tead4, TEA domain family member 4 (TEAD-4), Tcf13r1, ETF-related factor 2 (ETFR-2)) Copy Product Info

Synonyms: Transcriptional enhancer factor TEF-3, Tefr1, Tef3, TEF-1-related factor FR-19 (RTEF-1), TEF-1-related factor 1, Tead4, TEA domain family member 4 (TEAD-4), Tcf13r1, ETF-related factor 2 (ETFR-2)

Catalog No. TMPH-02943 Copy Product Info
TEAD4 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.7 kDa and the accession number is Q62296.
Other Forms of TEAD4 Protein, Mouse, Recombinant:
TEAD4 Protein, Human, Recombinant (His)
TEAD4 Protein, Human, Recombinant (His & Myc)
TEAD4 Protein, Mouse, Recombinant (His & Myc)
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Information

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
TEAD4 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.7 kDa and the accession number is Q62296.
Species
Mouse
Expression System
E. coli
TagTag Free
Accession NumberQ62296
Amino AcidRSIASSKLWMLEFSAFLERQQDPDTYNKHLFVHISQSSPSYSDPYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHIYRLVKE
Construction210-427 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTranscriptional enhancer factor TEF-3, Tefr1, Tef3, TEF-1-related factor FR-19 (RTEF-1), TEF-1-related factor 1, Tead4, TEA domain family member 4 (TEAD-4), Tcf13r1, ETF-related factor 2 (ETFR-2)
Research Background
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif. Might play a role in the embryonic development of skeletal muscle.
Chemical Properties
Molecular Weight25.7 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Dose Conversion

Keywords

Tefr 1Tef 3TEAD-4TEAD4Tead 4Tcf13r 1RTEF-1RTEF1ETFR-2ETFR2
Related Tags: TEAD4 Protein, Mouse, Recombinant chemical structure | TEAD4 Protein, Mouse, Recombinant molecular weight