α-Thujone [546-80-5]
Katalog-Nummer NB-64-43914-1mL
Size : 1mLx10mM(inDMSO)
Marke : Neo Biotech
α-Thujone (Synonyms: Thujone, ALPHA-(-)-THUJONE)
Catalog No. T8193 Copy Product Info
Purity: 98.41%
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
α-Thujone
Copy Product InfoSynonyms Thujone, ALPHA-(-)-THUJONE
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
Cas No. 546-80-5
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM. |
| Targets&IC50 | α7 nAChR:24.7μM |
| In vitro | In in-vivo one-trial passive avoidance paradigm show that thujone (1.25mg/kg, i.p.) significantly impaired nicotine-induced enhancement of learning and memory in Wistar rats[1]. |
| Synonyms | Thujone, ALPHA-(-)-THUJONE |
| Molecular Weight | 152.23 |
| Formula | C10H16O |
| Cas No. | 546-80-5 |
| Smiles | 11[C@]12C[C@]1(CC(=O)[C@@H]2C)C(C)C |
| Relative Density. | 0.914 g/mL at 20°C(lit.) |
| Storage | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 4.4 mg/mL (28.9 mM), Sonication is recommended.  | |||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (6.57 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||