Anti-Mast Cell Tryptase Antibody (8D176)
Katalog-Nummer NB-64-117828-100uL
Size : 100uL
Marke : Neo Biotech
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Anti-Mast Cell Tryptase Antibody (8D176)
(Synonyms: Tryptase skin, Tryptase III, tryptase I included, Tryptase I, tryptase beta I included, Tryptase beta 1, tryptase alpha/beta 1, tryptase alpha included, tryptase alpha II included, Tryptase alpha II, tryptase alpha I included, Tryptase alpha 1, Tryptase 1, TPSB1, TPSAB1 protein, TPSAB1, TPS2, TPS1, TPS 1, Skin tryptase, Pituitary tryptase, MCP 7, Mast cell protease II, Mast cell protease 7, Mast cell beta I tryptase, Mast cell alpha II tryptase, Lung tryptase, alpha II) Copy Product InfoSynonyms: Tryptase skin, Tryptase III, tryptase I included, Tryptase I, tryptase beta I included, Tryptase beta 1, tryptase alpha/beta 1, tryptase alpha included, tryptase alpha II included, Tryptase alpha II, tryptase alpha I included, Tryptase alpha 1, Tryptase 1, TPSB1, TPSAB1 protein, TPSAB1, TPS2, TPS1, TPS 1, Skin tryptase, Pituitary tryptase, MCP 7, Mast cell protease II, Mast cell protease 7, Mast cell beta I tryptase, Mast cell alpha II tryptase, Lung tryptase, alpha II
Catalog No. TMAC-02480 Copy Product Info
Anti-Mast Cell Tryptase Antibody (8D176) is a Rabbit antibody targeting Mast Cell Tryptase. Anti-Mast Cell Tryptase Antibody (8D176) can be used in IHC,IP,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Mast Cell Tryptase Antibody (8D176) is a Rabbit antibody targeting Mast Cell Tryptase. Anti-Mast Cell Tryptase Antibody (8D176) can be used in IHC,IP,WB. |
| Synonyms | Tryptase skin, Tryptase III, tryptase I included, Tryptase I, tryptase beta I included, Tryptase beta 1, tryptase alpha/beta 1, tryptase alpha included, tryptase alpha II included, Tryptase alpha II, tryptase alpha I included, Tryptase alpha 1, Tryptase 1, TPSB1, TPSAB1 protein, TPSAB1, TPS2, TPS1, TPS 1, Skin tryptase, Pituitary tryptase, MCP 7, Mast cell protease II, Mast cell protease 7, Mast cell beta I tryptase, Mast cell alpha II tryptase, Lung tryptase, alpha II |
| Ig Type | IgG |
| Clone | 8D176 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Mast Cell Tryptase on human skin lysates using anti-Mast Cell Tryptase antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-Mast Cell Tryptase antibody. Counter stained with hematoxylin.  , , , |
| Application | IHC IP WB |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast cell chymase, known as CMA1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19-amino acid signal peptide, an acidic 2-amino acid propeptide and a 226-amino acid catalytic domain. Tryptases comprise a family of trypsin-like serine proteases that are enzymatically active as heparin-stabilized tetramers. There are four functional genes for tryptase: α I, β I, β II and γ I, which map to human chromosome 16p13.3, with β tryptases representing the main isoenzymes expressed in mast cells. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID | Q15661 |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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