Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated

DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated

Drucken Drucken
Melden Sie sich an

Katalog-Nummer NB-64-96955-10ug

Size : 10ug

Marke : Neo Biotech


Remove All

DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: RDP, MDP, MBD1) Copy Product Info

Synonyms: RDP, MDP, MBD1

Catalog No. TMPY-07115 Copy Product Info
DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is P16444.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is P16444.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP16444
ConstructionA DNA sequence encoding the Human DPEP1 (P16444) (Met1-Ser385) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Protein Purity
≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from sterile 50 mM Tris, 100 mM NaCl, 8% Glycerol, 5% trehalose, pH 8.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
ReconstitutionPlease refer to the lot-specific COA.
SynonymsRDP, MDP, MBD1
Research Background
Dehydropeptidase-I, also known as DPEP1, is a kidney membrane enzyme. Its expression in normal colonic mucosa is very low, but it is highly expressed in colorectal adenoma and cancer specimens and is negatively correlated with parameters of pathological aggressiveness and poor prognosis. The overexpression of DPEP1 suppressed tumor cells invasiveness and increased sensitivity to chemotherapeutic agent Gemcitabine. Growth factor EGF treatment decreased DPEP1 expression. Dehydropeptidase-I may be a candidate target in PDAC for designing improved treatments. It uses zinc as a cofactor and acts as a disulfide-linked homodimer.
Chemical Properties
Molecular Weight44.32 kDa (predicted); 53 kDa (reducing contition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Dose Conversion

Related Tags: DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | DPEP1 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight