UGP2 Antibody - N-terminal region
Katalog-Nummer ARP48303_P050-25UL
Size : 25ul
Marke : Aviva Systems Biology
UGP2 Antibody - N-terminal region (ARP48303_P050)
| Datasheets/Manuals | Printable datasheet for anti-UGP2 (ARP48303_P050) antibody |
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| Tested Species Reactivity | Human |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human UGP2 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: TKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDN |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-UGP2 (ARP48303_P050) antibody is Catalog # AAP48303 (Previous Catalog # AAPY01673) |
| Sample Type Confirmation | UGP2 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Reference | Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007) |
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| Gene Symbol | UGP2 |
| Gene Full Name | UDP-glucose pyrophosphorylase 2 |
| Alias Symbols | UDPG, UGP1, DEE83, UDPGP, UGPP1, UGPP2, EIEE83, SVUGP2, UDPGP2, pHC379 |
| NCBI Gene Id | 7360 |
| Protein Name | UTP--glucose-1-phosphate uridylyltransferase |
| Description of Target | UGP2 is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme.The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q16851-2 |
| Protein Accession # | NP_001001521 |
| Nucleotide Accession # | NM_001001521 |
| Protein Size (# AA) | 497 |
| Molecular Weight | 56kDa |
| Protein Interactions | GLRX3; ARIH2; UGP2; UBC; NUSAP1; PUF60; PACSIN2; FAF1; PAPOLA; HSPH1; NUDC; CARM1; FARSB; USP15; RANBP3; HIRIP3; CUL1; CSDE1; ZYX; TARS; TROVE2; SET; PTPN12; PPP2R5C; PPM1G; PLOD2; CC2D1B; VASN; PARVA; ILK; GART; BUB1B; LYN; CBS; MROH2B; DNPEP; ISG15; ABC |