Creatinine is a breakdown product of creatine phosphate in muscle, produced at a relatively constant rate and excreted by the kidneys. Its serum concentration is widely used to assess kidney function, with elevated levels indicating impaired renal clearance. Assay kits for creatinine are designed for rapid, sensitive, and specific quantification in serum, plasma, urine, and other biological samples
Analytical Performance
- Sensitivity: Detection at low concentration.
- Linear Range
- Precision: Intra- and inter-assay CVs often below 5%.
Applications
- Clinical diagnostics: Assessing renal function, monitoring kidney disease, and evaluating muscle metabolism.
- Research: Studying metabolic disorders, drug toxicity, and physiological changes affecting creatinine levels.
- Sample Types: Validated for serum, plasma, urine, and sometimes saliva or cerebrospinal fluid.
Advantages
- High specificity and sensitivity
- Rapid and user-friendly protocols
- Compatibility with standard microplate readers
- Minimal sample preparation
Assay kits for creatinine provide reliable, rapid, and sensitive quantification in serum and other biological fluids. Assayc kits offer improved specificity and versatility over traditional chemical methods, supporting research into renal and metabolic health. Proper kit selection and protocol adherence are essential for optimal performance and accurate results.
