Human Myeloperoxidase (MPO) activation kit by CRISPRa

CAT#: GA102963

MPO CRISPRa kit - CRISPR gene activation of human myeloperoxidase



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MPO
Locus ID 4353
Kit Components

GA102963G1, Myeloperoxidase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102963G2, Myeloperoxidase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102963G3, Myeloperoxidase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000250
UniProt ID P05164
Synonyms Myeloperoxidase
Summary Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

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