Human sphingosine 1 phosphate phosphatase 1 (SGPP1) activation kit by CRISPRa

CAT#: GA113051

SGPP1 CRISPRa kit - CRISPR gene activation of human sphingosine-1-phosphate phosphatase 1



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol SGPP1
Locus ID 81537
Kit Components

GA113051G1, sphingosine 1 phosphate phosphatase 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113051G2, sphingosine 1 phosphate phosphatase 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113051G3, sphingosine 1 phosphate phosphatase 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_030791
UniProt ID Q9BX95
Synonyms SPPase1
Summary Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009]

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