MDC1 antibody

Cat# orb148033-100ug

Size : 100ug

Brand : Biorbyt

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MDC1 antibody

MDC1 antibody

Catalog Number: orb148033

Catalog Numberorb148033
CategoryAntibodies
DescriptionMouse monoclonal to MDC1 (ATTO-488). MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A. X on S139..
Species/HostMouse
ClonalityMonoclonal
Clone NumberP2B11
Tested applicationsICC, WB
ReactivityBovine, Human, Mouse, Primate
IsotypeIgG1
ImmunogenGST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
Concentration1 mg/ml
Dilution rangeWB (1:2000), ICC/IF (1:100)
ConjugationATTO-488
MW184kDa
TargetMDC1
Entrez240087
UniProt IDQ5PSV9
NCBINP_001010833.2
StorageConjugated antibodies should be stored at 4°C
Buffer/PreservativesPBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Alternative namesNuclear factor with BRCT domains1 antibody, mediat
NoteFor research use only
Application notes0.5 µg/ml of SMC-197 was sufficient for detection of MDC1 in 10 µg of HeLa cell lysate by ECL immunoblot analysis.
Expiration Date12 months from date of receipt.