SARS-CoV Spike Antibody
Cat# OAPB00218
Size : 0.1mg
Brand : Aviva Systems Biology
SARS-CoV Spike Antibody (OAPB00218)
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| Datasheets/Manuals | Printable datasheet for SARS-CoV Spike Antibody (OAPB00218) (OAPB00218) |
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| Predicted Species Reactivity | SARS-CoV-2 / COVID-19 Virus|Severe Acute Respiratory Syndrome Coronavirus|Virus |
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| Product Format | Liquid. SARS-CoV Spike antibody is supplied in PBS containing 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ELISA |
| Reconstitution and Storage | Stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Immunogen | Anti-SARS-CoV Spike antibody (3225) was raised against a peptide corresponding to 15 amino acids near the center of SARS-CoV Spike glycoprotein. The immunogen is located within amino acids 650-700 of SARS-CoV Spike. |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 40%, homology 56%) |
| Concentration | 1 mg/ml |
| Blocking Peptide | For anti-S (OAPB00218) antibody is Catalog # OEPB02312 |
| Application Info | SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 5 ng of free peptide at 1 ug/mL. |
| Reference | Marra et al. Science 2003;300:1399-404. Rota et al. Science 2003;300:1394-9. Navas-Nartin et al. J Neurovirol. 2004;10:75-85. Li et al. Nature 2003;426:450-4. |
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| Gene Symbol | S |
| Gene Full Name | spike glycoprotein |
| Alias Symbols | E2;Peplomer protein;sars2;spike glycoprotein. |
| NCBI Gene Id | 1489668 |
| Protein Name | Spike glycoprotein |
| Description of Target | Spike protein S1: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. |
| Uniprot ID | P59594 |
