TICAM1 Recombinant Protein
Cat# OPCD07436-200UG
Size : 200ug
Brand : Aviva Systems Biology
Datasheets/Manuals | Printable datasheet for TICAM1 Recombinant Protein (OPCD07436) |
---|
Predicted Species Reactivity | Mouse|Mus musculus |
---|---|
Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Ser263-Val526 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 97% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | Ticam1 |
---|---|
Gene Full Name | toll-like receptor adaptor molecule 1 |
Alias Symbols | AW046014;AW547018;TICAM;TICAM-1;TIR domain-containing adapter molecule 1;TIR domain-containing adapter protein inducing IFN-beta;TIR domain-containing adaptor inducing interferon-beta;toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta;Tr;TRIF. |
NCBI Gene Id | 106759 |
Protein Name | TIR domain-containing adapter molecule 1 |
Description of Target | Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. |
Uniprot ID | Q80UF7 |
Protein Accession # | NP_778154.1 |
Nucleotide Accession # | NM_174989.4 |
Protein Size (# AA) | Ser263~Val526 |
Molecular Weight | 39kDa |