SARS-CoV-2 - Spike protein - Antigens (proteins and peptides)

SARS-CoV-2 - Spike protein - Antigens (proteins and peptides)


The SARS-CoV-2 virus, the cause of the current Covid-19 pendemia, can infect human respiratory epithelial cells through an interaction with the human ACE2 receptor or angiotensin converting enzyme receptor 2. SARS-CoV-2 has on its surface a protein called Spike or S protein. This type I transmembrane protein is present on the viral envelope in the form of a homotrimer. Each monomer consists of 2 subunits, S1 and S2. The S1 subunit contains a receptor binding domain (RBD) which binds to the ACE2 receptor on the host membrane. The S2 sub-unit is activated by the bond between S1 and the ACE2 receptor and contains the elements necessary for membrane fusion. The S protein thus plays an important role in the infection of SARS-CoV-2 as well as in the induction of neutralizing antibody and T cell responses and in protective immunity.

Cat#
Description
Size
Price Excl. VAT
COV_VM5BD
 100 ug 
COV_VM4S1
 100 ug 
COV_VM5BD -1mg
 1 mg 
COV_VM4S1-1mg
 1 mg 
32-6253-50ug
 50ug 
32-6253-150ug
 150ug 
32-6251-0.25
 0,25mg 
32-6251-50
 50µg 
32-6253-150
 150µg 
32-6253-50
 50µg 
32-6272-150
 150µg 
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