™ 488 conjugate) Antibody (OAED00172) in Jurkat cells tissue/cell using Flow Cytometry" data-caption="Flow cytometry analysis of 106 Jurkat cells stained using HSP60 mAb (LK-2), DyLight 488 Conjugate at a concentration of 50 ug/ml
Datasheets/Manuals
Printable datasheet for Anti-HSP60 (LK-2) (DyLight™ 488 conjugate) Antibody (OAED00172)OAED00172
Product Info
Predicted Species Reactivity
Human, Mouse, Rat, Bovine, Bacteria, Dog, C
Clonality
Monoclonal
Clone
LK-2
Isotype
IgG1
Host
Mouse
Application
FC
Reconstitution and Storage
Long Term Storage : -20C
Immunogen
Recombinant human Hsp60.
Specificity
Recognizes human, mouse, rat, bovine, bacteria, dog, c. elegans, chicken, guinea pig, hamster, monkey, pig, plant and rabbit HSP60. Detects a band of ~60kDa by Western blot.
Formulation
Liquid. In PBS containing 0.09% sodium azide.
Purity
Protein G affinity purified.
Application Info
Flow Cytometry (1:20) Optimal conditions must be determined individually for each application.
Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.
Positive regulation of interferon-alpha production
11
Positive regulation of interferon-gamma production
61
Positive regulation of interleukin-10 production
32
Positive regulation of interleukin-12 production
39
Positive regulation of interleukin-6 production
63
Positive regulation of macrophage activation
18
Positive regulation of T cell activation
28
Positive regulation of T cell mediated immune response to tumor cell
3
Protein maturation
8
Protein refolding
11
Protein stabilization
64
Response to unfolded protein
47
T cell activation
68
Cellular components
Name
# of Products
Cell surface
369
Coated pit
38
Coated vesicle
2
Cyclin-dependent protein kinase activating kinase holoenzyme complex
6
Cytoplasm
4549
Cytosol
1868
Early endosome
107
Extracellular space
884
Lipopolysaccharide receptor complex
5
Mitochon
2
Mitochondrial inner membrane
251
Mitochondrial matrix
185
Protein function
Name
# of Products
ATP binding
2814
ATPase activity
285
Cell surface binding
163
Chaperone binding
213
DNA replication origin binding
28
Lipopolysaccharide binding
102
Nucleotide binding
3928
P53 binding
139
Protein binding
12191
Single-stranded DNA binding
136
Unfolded protein binding
252
Diseases
Name
# of Products
Disease mutation
5332
Hereditary spastic paraplegia
43
Leukodystrophy
62
Neurodegeneration
458
What is the species homology for "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Bovine, Bacteria, Dog, C".
How long will it take to receive "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 week".
What buffer format is "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)" provided in?
This item is provided in "". Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
This target may also be called "HLD4, CPN60, GROEL, HSP60, HSP65, SPG13, HSP-60, HuCHA60" in publications.
What is the shipping cost for "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
What is the guarantee for "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "". Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "HSPD1 Antibody - DyLight 488 Conjugated (OAED00172)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "HSPD1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "HSPD1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "HSPD1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "HSPD1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "HSPD1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "HSPD1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
Titration: 1.0 ug/ml Positive Control: Rat Muscle" data-size="300x300" class="product-image-wrapper cover">
Hspd1 Antibody - C-terminal region (ARP61107_P050)
Catalog #: ARP61107_P050
Species Tested: Human, Mouse, Rat
Application: WB
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Phone : +1 850 650 7790