Molecular cytogenetics
Molecular cytogenetics is a field of cytogenetics developing techniques, based on DNA sequence homologies, allowing the specific identification of all or part of one or more chromosomes.
Molecular cytogenetics which is a karyotype complementary technique based on in situ hybridization.
The principle is based on the use of a molecular probe, ie a small sequence of DNA (or RNA) whose normal location is known in the genome and which is chemically labeled to can be identified later. This probe is brought into contact with the chromosomes of a mitosis (or interphase nuclei) and will hybridize (bind) specifically at the level of its complementary sequence. The probe can then be viewed under a microscope whose location precisely identifies the chromosomal region of which it is complementary.
The probes used for the in situ hybridization identify either repeated sequences (long arm of the Y, specific or non-specific centromeric alphoid probes, non-specific telomeric probes), or unique sequences (locus or regional probes), or a mixture of unique sequences hybridizing on all or part of a chromosome (total or partial paint probes).
Frequently Asked Questions (FAQ)
Where can I find molecular cytogenetics products on the CliniSciences website?
molecular cytogenetics products are available in this section and can be sorted by product families or sub-categories, such as In situ hybridization probes. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.
What types of products are available in the molecular cytogenetics category?
The molecular cytogenetics category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The In situ hybridization probes sub-categories allow you to find the products that meet your needs more quickly.
How can I quickly find a molecular cytogenetics product?
To find a molecular cytogenetics product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.
Does CliniSciences stock several product codes in the molecular cytogenetics category?
Yes, CliniSciences distributes several product references in the molecular cytogenetics category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.
Can I request a quote for molecular cytogenetics products?
Yes, you can request a quote for molecular cytogenetics products from the product page or by contacting CliniSciences (info@clinisciences.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.
How can I find out if a molecular cytogenetics product is available to order?
The availability of a molecular cytogenetics product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact CliniSciences with the product code or name of the product you are looking for.
What should I do if I cannot find the molecular cytogenetics product I am looking for?
If the molecular cytogenetics product you are looking for does not appear in the catalogue, please contact CliniSciences with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.
Are all molecular cytogenetics products available under the same terms and conditions?
No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.