CCR8 antibody

Cat# GTX21666-100ug

Size : 100ug

Brand : Genetex

Contact local distributor :


Phone : +1 850 650 7790

Anti-CCR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX21666

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, FACS, ELISA, Neutralizing/Inhibition

Reactivity

Human, Mouse
Package
100 μg
View product citations for antibody GTX21666 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
IHC-P 1:125
FACS 2-6μl/10⁶cells/50-100μl
ELISA 1:50,000
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Product Note

Peptide sequence is <50 % identical to other human chemokine receptors in this region.

PROPERTIES

Form

Liquid

Buffer

10mM KHPO₄, 140mM NaCl, 1mg/ml BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide VTDYYYPDIFSSPCDAELIQTNGKL-C corresponding to aa 12-36 of human CCR8

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CC motif chemokine receptor 8,CCCKR8,CCR8,CDw198,CKRL1,CMKBR8,CMKBRL2,CY6,GPRCY6,TER1,CD198,C-C motif chemokine receptor 8

Cellular Localization

Cell membrane

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES

Anti-CCR8 antibody used in IHC (Paraffin sections) (IHC-P). GTX21666

GTX21666 IHC-P Image

IHC-P analysis of human spleen tissue using GTX21666 CCR8 antibody.

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REVIEW

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