Reagents and instruments for immunology, cell biology and molecular biology.

α-Thujone [546-80-5]

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Cat# T8193-10mg

Size : 10mg

Brand : TargetMol

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α-Thujone (Synonyms: Thujone, ALPHA-(-)-THUJONE)

α-Thujone

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Synonyms Thujone, ALPHA-(-)-THUJONE

Cas No. 546-80-5

For research use only—not for human use. No sales to individuals. Use as intended only.

Batch Information

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Purity:98.41%

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COA HNMR

Product Introduction

Bioactivity

Description	α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
Targets&IC50	α7 nAChR:24.7μM
In vitro	In in-vivo one-trial passive avoidance paradigm show that thujone (1.25mg/kg, i.p.) significantly impaired nicotine-induced enhancement of learning and memory in Wistar rats[1].
Synonyms	Thujone, ALPHA-(-)-THUJONE

Chemical Properties

Molecular Weight	152.23
Formula	C₁₀H₁₆O
Cas No.	546-80-5
Smiles	05[C@]12C[C@]1(CC(=O)[C@@H]2C)C(C)C
Relative Density.	0.914 g/mL at 20°C(lit.)

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 4.4 mg/mL (28.9 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (6.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5690 mL	32.8450 mL	65.6901 mL	328.4504 mL
5 mM	1.3138 mL	6.5690 mL	13.1380 mL	65.6901 mL
10 mM	0.6569 mL	3.2845 mL	6.5690 mL	32.8450 mL
20 mM	0.3285 mL	1.6423 mL	3.2845 mL	16.4225 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.