General Info
| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-BPI is suitable for use in ELISA research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 4H5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration: | 100 ug/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
Description
| Tissue Specificity | Restricted to cells of the myeloid series. |
| Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
| Protein Name | Bactericidal Permeability-Increasing ProteinBpiCap 57 |
| Database Links | Reactome: R-HSA-166016Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
| Alternative Antibody Names | Anti-Bactericidal Permeability-Increasing Protein antibodyAnti-Bpi antibodyAnti-Cap 57 antibodyAnti-BPI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance