General Info
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BZW2 (190-300) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | BZW2 |
Gene ID: | 28969 |
Uniprot ID: | 5MP1_HUMAN |
Immunogen Region: | 190-300 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-300 of human BZW2 (NP_054757.1). |
Immunogen Sequence: | LFKAWMAEKDANSVTSSLRK ANLDKRLLELFPVNRQSVDH FAKYFTDAGLKELSDFLRVQ QSLGTRKELQKELQERLSQE CPIKEVVLYVKEEMKRNDLP ETAVIGLLWTC |
Description
Function | Translation initiation regulator which represses non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function. Increases the accuracy of translation initiation by impeding EIF5-dependent translation from non-AUG codons by competing with it for interaction with EIF2S2 within the 43S pre-initiation complex (PIC) in an EIF3C-binding dependent manner. |
Protein Name | Eif5-Mimic Protein 1Basic Leucine Zipper And W2 Domain-Containing Protein 2 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Eif5-Mimic Protein 1 antibodyAnti-Basic Leucine Zipper And W2 Domain-Containing Protein 2 antibodyAnti-BZW2 antibodyAnti-5MP1 antibodyAnti-HSPC028 antibodyAnti-MSTP017 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance