Reagents and instruments for immunology, cell biology and molecular biology.
 
> Anti-CD68 antibody (171-220 Internal)

Anti-CD68 antibody (171-220 Internal)

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Cat# NB-22-6573-200ul

Size : 200µg

Brand : Neo Biotech

Contact local distributor :


Phone : +1 850 650 7790

  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Western blot analysis of lysate from mouse spleen cells, using CD68 Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100
  • Western blot analysis of mouse spleen cells using CD68 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

General Info

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Macrosialin (171-220 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Information

Gene Symbol: CD68
Gene ID: 968
Uniprot ID: CD68_HUMAN
Immunogen Region: 171-220 aa
Specificity: CD68 Polyclonal Antibody detects endogenous levels of CD68 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD68 at the amino acid range 171-220

Description

Post Translational Modifications N- and O-glycosylated.
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Protein Name Macrosialin
Gp110
Cd Antigen Cd68
Database Links Reactome: R-HSA-6798695
Cellular Localisation Isoform Short: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Long: Endosome Membrane
Lysosome Membrane
Alternative Antibody Names Anti-Macrosialin antibody
Anti-Gp110 antibody
Anti-Cd Antigen Cd68 antibody
Anti-CD68 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance