General Info
| Host: | Rabbit |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-Myeloperoxidase is suitable for use in Immunohistochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | SP72 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Dilution Range: | IHC-P 1:25-1:100 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
| Gene Symbol: | MPO |
| Gene ID: | 4353 |
| Uniprot ID: | PERM_HUMAN |
Description
| Function | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage. |
| Protein Name | MyeloperoxidaseMpo Cleaved Into - Myeloperoxidase - 89 Kda Myeloperoxidase - 84 Kda Myeloperoxidase - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8941413 |
| Cellular Localisation | Lysosome |
| Alternative Antibody Names | Anti-Myeloperoxidase antibodyAnti-Mpo Cleaved Into - Myeloperoxidase - 89 Kda Myeloperoxidase - 84 Kda Myeloperoxidase - Myeloperoxidase Light Chain - Myeloperoxidase Heavy Chain antibodyAnti-MPO antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance