Anti-NRG1 Beta 1 Antibody (1T318)
Cat# NB-64-121068-100uL
Size : 100uL
Brand : Neo Biotech
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Anti-NRG1 Beta 1 Antibody (1T318)
(Synonyms: SMDF, NRG1-IT2, NRG1 β1, Neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA) Copy Product InfoSynonyms: SMDF, NRG1-IT2, NRG1 β1, Neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA
Catalog No. TMAY-00060 Copy Product Info
Anti-NRG1 Beta 1 Antibody (1T318) is a Mouse antibody targeting NRG1 Beta 1. Anti-NRG1 Beta 1 Antibody (1T318) can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-NRG1 Beta 1 Antibody (1T318) is a Mouse antibody targeting NRG1 Beta 1. Anti-NRG1 Beta 1 Antibody (1T318) can be used in WB. |
| Synonyms | SMDF, NRG1-IT2, NRG1 β1, Neuregulin 1, NDF, MSTP131, MST131, HRGA, HRG1, HRG, HGL, GGF2, GGF, ARIA |
| Ig Type | Mouse IgG2b |
| Clone | 1T318 |
| Reactivity | Human |
| Specificity | Human Neuregulin-1/NRG1 No cross-reactivity in WB with Human NRG1-alpha |
| Verified Activity | Anti-NRG1-beta 1 mouse monoclonal antibody at 1:500Lane A: Human NRG1-beta1 (100ng) -Lane B: Human NRG1-alpha (100ng) -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Performed under reducing conditions. |
| Application | WB |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, a synthetic peptide corresponding to the center region of the human NRG1 isoform beta 1. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | A synthetic peptide: center region of the human NRG1 isoform beta 1. |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Keywords
MSTP-131MSTP 131MST-131MST 131HRG-1HRG 1GGF-2GGF 2
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Related Tags: Anti-NRG1 Beta 1 Antibody (1T318) chemical structure
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