Caspase 5 (Ich-3, ICErel-III, TY) (AP)

Caspase 5/Ich-3/Ty/ICErel-III belongs to the ICE family of cysteine proteases. Its expression is enhanced during the septic shock. Over-expression of Caspase 5 can induce apoptosis. It is processed through Granzyme-B.

Suitable for use in Western Blot. Other applications not tested.

Western Blot: 2.5-5ug/ml for 2hrs at RT
Optimal dilutions to be determined by the researcher.

Positive Control: Jurkat cells

May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Note: Applications are based on unconjugated antibody.

Pab

IgG

rabbit

human

As reported

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purified by Protein A affinity chromatography.

A synthetic peptide derived from the middle of human Caspase 5.

Middle region Cellular Localization

Recognizes Caspase 5. May recognize p38 and p30 cleavage determinants. MW of Antigen

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.