CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, CD11b, ITGAM, CR3A, Integrin alphaM, CR-3alpha, CR3alpha) (PerCP/Cy5.5)

Cat# 367025-25T

Size : 25Tests

Brand : US Biological



367025 CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, CD11b, ITGAM, CR3A, Integrin alphaM, CR-3alpha, CR3alpha) (PerCP/Cy5.5)

Clone Type
Monoclonal
Host
mouse
Source
human
Swiss Prot
P11215
Isotype
IgG2b,k
Grade
Highly Purified
Applications
FC
Crossreactivity
Hu
Accession #
NM_000632
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

CD11b is a 165kD adhesion glycoprotein that associates with the 95kD integrin beta2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody is directed against the CD11b antigen on human monocytes and granulocytes.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 5ul strains 1x10e6 cells in a 100ul staining volume or 100ul of whole blood
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. PerCP conjugates are sensitive to light.

Applications
Product Type: Mab|Isotype: IgG2b,k|Clone No: OKM2|Host: mouse|Source: human|Concentration: ~0.05mg/ml|Form: Supplied as a liquid in PBS, pH 7.2, 0.2% BSA, 0.09% sodium azide. Labeled with PerCP/Cy5.5. |Purity: Highly Purified|Immunogen: Human lymph node lymphocytes|Specificity: Recognizes human CD11B. ||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Human lymph node lymphocytes
Form
Supplied as a liquid in PBS, pH 7.2, 0.2% BSA, 0.09% sodium azide. Labeled with PerCP/Cy5.5.
Purity
Highly Purified
Specificity
Recognizes human CD11B.
References
1. Cywes C, et al. 1996. Infect Immun. 64:5373. 2. Hoffman R.A, et al. 1980. Proc Natl Acad Sci USA. 77:4914. 3. Kim Y.R, et al. 1991. Leuk Res. 15:409. 4. Manzano L, et al. 1992. Gut. 33:246. 5. Scott C.S, et al. 1990. Eur J Haematol. 44:24. 6. Szucs G, et al. 1994. Scand J Immunol. 40:481.