- More Files
Western Blot (Recombinant protein)
Western blot analysis using CSF1 monoclonal antibody, clone 2D10 (Cat # MAB10616) against human recombinant CSF2 (1) and CSF1 (2) .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human placenta tissues using CSF1 monoclonal antibody, clone 2D10 (Cat # MAB10616) .
- Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CSF1.
Immunogen
Recombinant protein corresponding to human CSF1.
Host
Mouse
Theoretical MW (kDa)
60
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Western Blot (Recombinant protein)
Western blot analysis using CSF1 monoclonal antibody, clone 2D10 (Cat # MAB10616) against human recombinant CSF2 (1) and CSF1 (2) .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human placenta tissues using CSF1 monoclonal antibody, clone 2D10 (Cat # MAB10616) .Enzyme-linked Immunoabsorbent Assay
- Gene Info — CSF1
Entrez GeneID
1435Gene Name
CSF1
Gene Alias
MCSF, MGC31930
Gene Description
colony stimulating factor 1 (macrophage)
Omim ID
120420Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000013362|OTTHUMP00000013363|OTTHUMP00000013364|colony stimulating factor 1|macrophage colony stimulating factor
- Interactome
- Pathway
- Disease
- Publication Reference
- Interleukin-34 is present at the fetal-maternal interface and induces immunoregulatory macrophages of a decidual phenotype in vitro.
Lindau R, Mehta RB, Lash GE, Papapavlou G, Boij R, Berg G, Jenmalm MC, Ernerudh J, Svensson-Arvelund J.
Human Reproduction 2018 Apr; 33(4):588.
Application：IHC-P, Human, Placenta, Decidua.
- The Human Fetal Placenta Promotes Tolerance against the Semiallogeneic Fetus by Inducing Regulatory T Cells and Homeostatic M2 Macrophages.
Svensson-Arvelund J, Mehta RB, Lindau R, Mirrasekhian E, Rodriguez-Martinez H, Berg G, Lash GE, Jenmalm MC, Ernerudh J.
The Journal of Immunology 2015 Feb; 194(4):1534.
- Interleukin-34 is present at the fetal-maternal interface and induces immunoregulatory macrophages of a decidual phenotype in vitro.