GAPDH antibody [GT239]
Cat# GTX627408-100ul
Size : 100ul
Brand : Genetex
Contact local distributor :
Phone : +1 850 650 7790
![Anti-GAPDH antibody [GT239] used in Western Blot (WB). GTX627408](http://www.genetex.com/templates/default/js/lightbox/images/loading.gif "Anti-GAPDH antibody [GT239] used in Western Blot (WB). GTX627408")
6
Host | Mouse |
|---|---|
Clonality | Monoclonal |
Clone Name | GT239 |
Isotype | IgG2b |
Application | WB, ICC/IF, IHC-P, EMSA |
Reactivity | Human, Mouse, Rat, Zebrafish, Yeast, Drosophila, Dog, Hamster, Pig, Monkey, Candida albicans, E. coli, Chinese Hamster |
| Package | 100 μl, 25 μl |
Datasheet File View product citations for antibody GTX627408 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:20000 |
| ICC/IF | 1:100-1:1000 |
| IHC-P | 1:100-1:1000 |
| EMSA | Assay dependent |
Not tested in other applications.
Calculated MW
36 kDa. ( Note )
Positive Control
NIH-3T3 , mouse brain , PC-12 , rat brain , coli M15 , 293T , A431 , HeLa , HepG2
Predict Reactivity
Rabbit, Sheep, Bovine, Cat, Chicken, Guinea pig, Xenopus tropicalis, Rhesus Monkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein encompassing a sequence within the center region of human GAPDH. The exact sequence is proprietary.
Purification
Affinity purified by Protein G.
Conjugation
Unconjugated
RRID
AB_11174761
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
glyceraldehyde-3-phosphate dehydrogenase , G3PD , GAPD , HEL-S-162eP
Cellular Localization
Cytoplasm , perinuclear region , Membrane
Background
The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome. [provided by RefSeq]
Database
DATA IMAGES
| | GTX627408 WB Image GAPDH antibody [GT239] detects GAPDH protein by western blot analysis. |
| | GTX627408 WB ImageWhole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 WB Image Sample (30 μg of whole cell lysate) |
| | GTX627408 ICC/IF ImageGAPDH antibody [GT239] detects GAPDH protein at cytoplasm by immunofluorescent analysis.Sample: HeLa cells were fixed in ice-cold MeOH for 5 min.Green: GAPDH stained by GAPDH antibody [GT239] (GTX627408) diluted at 1:500.Blue: Hoechst 33342 staining. |
| | GTX627408 WB ImageVarious tissue extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 IHC-P ImageGAPDH antibody [GT239] detects GAPDH protein at cytoplasm by immunohistochemical analysis.Sample: Paraffin-embedded mouse kidney.GAPDH stained by GAPDH antibody [GT239] (GTX627408) diluted at 1:200.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min |
| | GTX627408 WB ImageVarious whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:10000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 WB Image GAPDH antibody [GT239] detects GAPDH protein by western blot analysis. |
| | GTX627408 WB Image GAPDH antibody [GT239] detects GAPDH protein by western blot analysis. |
| | GTX627408 WB ImageWhole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 WB ImageWhole cell extract (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 WB ImageVarious whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:10000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 WB ImageVarious whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GAPDH antibody [GT239] (GTX627408) diluted at 1:10000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. |
| | GTX627408 WB ImageThe data was published in the journal Oncotarget in 2015.PMID: 26327325 |
| | GTX627408 WB ImageThe data was published in the Nat Commun in 2020. PMID: 33257668 |
| | GTX627408 WB ImageThe data was published in the journal Front Physiol in 2019. PMID: 31681015 |
| | GTX627408 WB ImageThe data was published in the journal Biomed Res Int in 2015. PMID: 26448933 |
| | GTX627408 WB ImageThe data was published in the journal Biomed Res Int in 2015. PMID: 26448933 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2016. PMID: 27832139 |
| | GTX627408 WB ImageThe data was published in the J Cell Mol Med in 2020. PMID: 32827244 |
| | GTX627408 WB ImageThe data was published in the J Cell Mol Med in 2020. PMID: 32827244 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2015.PMID: 26681405 |
| | GTX627408 WB ImageThe data was published in the journal EMBO Mol Med in 2013.PMID: 23828861 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2016.PMID: 27681590 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal Front Neurol in 2019.PMID: 31258504 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2013.PMID: 24282540 |
| | GTX627408 WB ImageThe data was published in the journal J Cell Mol Med in 2015.PMID: 25683605 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2019.PMID: 31337756 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2020.PMID: 32150830 |
| | GTX627408 WB ImageThe data was published in the journal Cell Death Dis in 2020.PMID: 32034133 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2017.PMID: 28198375 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2018.PMID: 29933620 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2018.PMID: 30030436 |
| | GTX627408 WB ImageThe data was published in the journal J Cancer Sci Ther in 2018.PMID: 29780443 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2017.PMID: 28747643 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2020.PMID: 32150830 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2015.PMID: 26681405 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2020.PMID: 32150830 |
| | GTX627408 WB ImageThe data was published in the journal Cell Death Dis in 2020.PMID: 32034133 |
| | GTX627408 WB ImageThe data was published in the journal Oncotarget in 2016.PMID: 27708250 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2018.PMID: 29933620 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2018.PMID: 29933620 |
| | GTX627408 WB ImageThe data was published in the journal Curr Biol in 2017.PMID: 28966089 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2019.PMID: 30898877 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2015.PMID: 26681405 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2014.PMID: 24718614 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2016.PMID: 27681590 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2018.PMID: 29933620 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2016.PMID: 27307030 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2015.PMID: 26681405 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2017.PMID: 29038428 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2016.PMID: 27492621 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2015.PMID: 26681405 |
| | GTX627408 WB ImageThe data was published in the journal J Cancer Sci Ther in 2018.PMID: 29780443 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2018.PMID: 29933620 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2016.PMID: 27681590 |
| | GTX627408 WB ImageThe data was published in the journal Oxid Med Cell Longev in 2020.PMID: 32089770 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2013.PMID: 23977396 |
| | GTX627408 WB ImageThe data was published in the journal Front Neurol in 2019.PMID: 31258504 |
| | GTX627408 WB ImageThe data was published in the journal Oncotarget in 2018.PMID: 29581854 |
| | GTX627408 WB ImageThe data was published in the 2022 in Sci Rep. PMID: 35484165 |
| | GTX627408 WB ImageThe data was published in the 2022 in Pathogens. PMID: 35335638 |
| | GTX627408 WB ImageThe data was published in the 2022 in Sci Rep. PMID: 35484165 |
| | GTX627408 WB ImageThe data was published in the 2022 in Pathogens. PMID: 35335638 |
| | GTX627408 WB ImageThe data was published in the 2020 in Cell Commun Signal. PMID: 33228717 |
| | GTX627408 WB ImageThe data was published in the 2020 in Cell Commun Signal. PMID: 33228717 |
| | GTX627408 WB ImageThe data was published in the 2020 in Cell Commun Signal. PMID: 33228717 |
| | GTX627408 WB ImageThe data was published in the 2020 in Cell Commun Signal. PMID: 33228717 |
| | GTX627408 WB ImageThe data was published in the 2022 in Int J Mol Sci. PMID: 35054778 |
| | GTX627408 WB ImageThe data was published in the 2020 in Cell Commun Signal. PMID: 33228717 |
| | GTX627408 WB ImageThe data was published in the 2020 in PLoS One. PMID: 32163428 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2014. PMID: 25166596 |
| | GTX627408 WB ImageThe data was published in the journal Nucleic Acids Res in 2013. PMID: 23658231 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2014. PMID: 25166596 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2014. PMID: 25166596 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2014. PMID: 25166596 |
| | GTX627408 WB ImageThe data was published in the journal Cell Death Dis in 2017. PMID: 29238067 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31835799 |
| | GTX627408 WB ImageThe data was published in the journal Oncogene in 2017. PMID: 28319065 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2017. PMID: 29273797 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol Commun in 2019. PMID: 30626447 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2015. PMID: 26151845 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol Commun in 2019. PMID: 30626447 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2015. PMID: 26151845 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol Commun in 2019. PMID: 30626447 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol Commun in 2019. PMID: 30626447 |
| | GTX627408 WB ImageThe data was published in the journal Cardiovasc Diabetol in 2018. PMID: 29903013 |
| | GTX627408 WB ImageThe data was published in the journal Front Cell Neurosci in 2014. PMID: 25071443 |
| | GTX627408 WB ImageThe data was published in the 2022 in Nat Commun. PMID: 35618735 |
| | GTX627408 WB ImageThe data was published in the 2016 in PLoS Genet. PMID: 27727273 |
| | GTX627408 WB ImageThe data was published in the 2022 in Nat Commun. PMID: 35618735 |
| | GTX627408 WB ImageThe data was published in the 2022 in Nat Commun. PMID: 35618735 |
| | GTX627408 WB ImageThe data was published in the 2022 in EMBO Mol Med. PMID: 35253392 |
| | GTX627408 WB ImageThe data was published in the 2022 in Front Aging Neurosci. PMID: 35264943 |
| | GTX627408 WB ImageThe data was published in the 2022 in Front Aging Neurosci. PMID: 35264943 |
| | GTX627408 WB ImageThe data was published in the 2016 in PLoS Genet. PMID: 27727273 |
| | GTX627408 WB ImageThe data was published in the 2021 in Nat Commun. PMID: 33712616 |
| | GTX627408 WB ImageThe data was published in the J Cell Mol Med in 2020. PMID: 32827244 |
| | GTX627408 WB ImageThe data was published in the J Cell Mol Med in 2020. PMID: 32827244 |
| | GTX627408 WB ImageThe data was published in the journal J Virol in 2017. PMID: 28679762 |
| | GTX627408 WB ImageThe data was published in the journal J Virol in 2017. PMID: 28679762 |
| | GTX627408 WB ImageThe data was published in the journal Biomed Res Int in 2014. PMID: 25162007 |
| | GTX627408 WB ImageThe data was published in the journal Commun Biol in 2019. PMID: 31754649 |
| | GTX627408 WB ImageThe data was published in the journal Biomed Res Int in 2014. PMID: 25162007 |
| | GTX627408 WB ImageThe data was published in the journal Biomed Res Int in 2014. PMID: 25162007 |
| | GTX627408 WB ImageThe data was published in the journal Biomed Res Int in 2014. PMID: 25162007 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2017. PMID: 28134239 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2017. PMID: 28134239 |
| | GTX627408 WB ImageThe data was published in the journal eNeuro in 2017. PMID: 28856243 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2018. PMID: 29444136 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2014. PMID: 24406502 |
| | GTX627408 WB ImageThe data was published in the journal Mol Oncol in 2017. PMID: 28100038 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2017. PMID: 28829370 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2017. PMID: 28829370 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2018. PMID: 29444136 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2017. PMID: 28157211 |
| | GTX627408 WB ImageThe data was published in the journal Front Cell Neurosci in 2014. PMID: 25071443 |
| | GTX627408 WB ImageThe data was published in the journal Front Cell Neurosci in 2014. PMID: 25071443 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol in 2018. PMID: 28780615 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol in 2018. PMID: 28780615 |
| | GTX627408 WB ImageThe data was published in the journal Nat Commun in 2016. PMID: 27460411 |
| | GTX627408 WB ImageThe data was published in the journal Acta Neuropathol in 2018. PMID: 28780615 |
| | GTX627408 WB ImageThe data was published in the journal PLoS One in 2015. PMID: 26110811 |
| | GTX627408 WB ImageThe data was published in the journal Oncogene in 2017. PMID: 28319065 |
| | GTX627408 WB ImageThe data was published in the journal Hum Mol Genet in 2015. PMID: 26085575 |
| | GTX627408 WB ImageThe data was published in the journal Cell Death Dis in 2017. PMID: 29238067 |
| | GTX627408 WB ImageThe data was published in the journal Oncogene in 2017. PMID: 28319065 |
| | GTX627408 WB ImageThe data was published in the journal ASN Neuro in 2013.PMID: 24286475 |
| | GTX627408 WB ImageThe data was published in the journal Sci Rep in 2016.PMID: 27222304 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal Front Neurol in 2019.PMID: 31258504 |
| | GTX627408 WB ImageThe data was published in the journal J Biol Chem in 2016.PMID: 26742848 |
| | GTX627408 WB ImageThe data was published in the journal Oxid Med Cell Longev in 2020.PMID: 32089770 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31311187 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31835799 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31311187 |
| | GTX627408 WB ImageThe data was published in the journal Cell Death Dis in 2017. PMID: 29238067 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31311187 |
| | GTX627408 WB ImageThe data was published in the journal Cells in 2019. PMID: 31766533 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31311187 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31835799 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2020. PMID: 31947604 |
| | GTX627408 WB ImageThe data was published in the journal Cell Death Dis in 2017. PMID: 29238067 |
| | GTX627408 WB ImageThe data was published in the journal Cells in 2019. PMID: 31766533 |
| | GTX627408 WB ImageThe data was published in the journal Cardiovasc Diabetol in 2018. PMID: 29903013 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31835799 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2019. PMID: 31323961 |
| | GTX627408 WB ImageThe data was published in the journal Int J Mol Sci in 2019. PMID: 31323961 |
| | GTX627408 WB ImageThe data was published in the journal Cells in 2019. PMID: 31640218 |
| | GTX627408 WB ImageThe data was published in the journal Cells in 2019. PMID: 31766533 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31835799 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31311187 |
| | GTX627408 WB ImageThe data was published in the journal Molecules in 2017. PMID: 28531143 |
| | GTX627408 WB ImageThe data was published in the journal Cancers (Basel) in 2019. PMID: 31835799 |
| | GTX627408 WB ImageThe data was published in the journal Oncotarget in 2017. PMID: 27926533 |
| | GTX627408 WB ImageThe data was published in the journal Oncogene in 2017. PMID: 28319065 |
Application Reference
CP Chen et al. Heliyon 2024; 10 (7) : 29055 Synergistic effects of the combination of trametinib and alpelisib in anaplastic thyroid cancer with BRAF and PI3KCA co-mutations
Application : WB
YL Chen et al. Viruses 2024; 16 : 523 Novel Anti-Viral Properties of the Herbal Extract of Davallia mariesii against Influenza A Virus
Y?ld?z A et al. Mol Ther Nucleic Acids 2024; 35 (2) : 102162 Trans-amplifying RNA expressing functional miRNA mediates target gene suppression and simultaneous transgene expression.
TP Martinez et al. eNeuro (2024) et al. TP Martinez et al. eNeuro (2024) 2024; 11 (3) : ENEURO.0175-23.2024 Amyloid-β-induced dendritic spine elimination requires Ca2+-permeable AMPA receptors, AKAP-Calcineurin-NFAT signaling, and the NFAT target gene Mdm2
Application : WB
W-F Tang et al. Antimicrob Agents Chemother 2024; : e0095623 BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir
Submit a Reference Application : WB
REVIEW
GAPDH antibody [GT239] Cat. No. GTX627408
| Rating | | ( Average 4.5 based on 6 users reviews) |
| Western Blot(WB) | | ( Average 4.5 based on 6 users reviews) |
Application Reference
CP Chen et al. Heliyon 2024; 10 (7):29055 Synergistic effects of the combination of trametinib and alpelisib in anaplastic thyroid cancer with BRAF and PI3KCA co-mutations
Application : WB
YL Chen et al. Viruses 2024; 16:523 Novel Anti-Viral Properties of the Herbal Extract of Davallia mariesii against Influenza A Virus
Y?ld?z A et al. Mol Ther Nucleic Acids 2024; 35 (2):102162 Trans-amplifying RNA expressing functional miRNA mediates target gene suppression and simultaneous transgene expression.
TP Martinez et al. eNeuro (2024) et al. TP Martinez et al. eNeuro (2024) 2024; 11 (3):ENEURO.0175-23.2024 Amyloid-β-induced dendritic spine elimination requires Ca2+-permeable AMPA receptors, AKAP-Calcineurin-NFAT signaling, and the NFAT target gene Mdm2
Application : WB
W-F Tang et al. Antimicrob Agents Chemother 2024;:e0095623 BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir
Application : WB
G Mendez-Callejas et al. Plants 2024; 13 (5):570 Natural 2′,4-Dihydroxy-4′,6′-dimethoxy Chalcone Isolated from Chromolaena tacotana Inhibits Breast Cancer Cell Growth through Autophagy and Mitochondrial Apoptosis
Application : WB
Timson RC et al. J Biol Chem 2024; 300 (2):105645 Development of a mouse model expressing a bifunctional glutathione-synthesizing enzyme to study glutathione limitation in?vivo.
S Yamaoka et al. Biochem Biophys Rep 2024; 37:101637 RelA and mitogen-activated protein kinase kinase kinases potently enhance lentiviral vector production
Application : WB
Cummings SE et al. iScience 2024; 27 (1):108708 SARS-CoV-2 antigen-carrying extracellular vesicles activate T?cell responses in a human immunogenicity model.
Schmit MM et al. Open Biol 2024; 14 (1):230407 A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells.
Hansen FM et al. Life Sci Alliance 2024; 7 (2) Mitochondrial phosphoproteomes are functionally specialized across tissues.
Perego MC et al. Toxicol Res (Camb) 2023; 12 (2):296-309 Arsenic impairs stem cell differentiation via the Hippo signaling pathway.
D??ng TB et al. Toxicol Appl Pharmacol 2023; 461:116386 2,4-di-tert-butylphenol exposure impairs osteogenic differentiation.
Leung W et al. Cell Rep 2023; 42 (12):113523 FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination.
Toyoda JH et al. Int J Mol Sci 2023; 25 (1) Hexavalent Chromium Targets Securin to Drive Numerical Chromosome Instability in Human Lung Cells.
H Heo et al. Autophagy 2023;:1-16 TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1
Zhang A et al. Cancer Res Commun 2023; 3 (11):2358-2374 Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers.
Schmidt S et al. Nat Commun 2023; 14 (1):7674 A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
JD Garcia et al. iScience 2023; Distinct mechanisms drive sequential internalization and degradation of GABAARs during global ischemia and reperfusion injury
Application : WB
X Meng et al. Nature 2023; Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment
Application : WB
Power AS et al. bioRxiv 2023; Nitric Oxide modulates spontaneous Ca (2+) release and ventricular arrhythmias during β-adrenergic signalling through S -nitrosylation of Calcium/Calmodulin dependent kinase II.
Le CT et al. Endocrinol Metab (Seoul) 2023; 38 (4):395-405 Phloretin Ameliorates Succinate-Induced Liver Fibrosis by Regulating Hepatic Stellate Cells.
Hung YH et al. Am J Cancer Res 2023; 13 (8):3417-3432 Pancreatic cancer cell-derived semaphorin 3A promotes neuron recruitment to accelerate tumor growth and dissemination.
M Yousefi et al. Emerg Microbes Infect 2023;:2256416 Betacoronaviruses SARS-CoV-2 and HCoV-OC43 Infections in IGROV-1 Cell Line Require Aryl Hydrocarbon Receptor
Application : WB
Huang SE et al. Theranostics 2023; 13 (12):4059-4078 Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases.
Liang W et al. Nat Commun 2023; 14 (1):5031 Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired.
Zengel J et al. Nat Methods 2023; 20 (7):1070-1081 Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.
JL Yeh et al. Biomed Pharmacother 2023; 165:115109 Xanthine derivative KMUP-1 ameliorates retinopathy
Application : WB
Reactivity : Mouse
Zhao B et al. Cell Oncol (Dordr) 2023; 46 (3):717-733 USP13 promotes breast cancer metastasis through FBXL14-induced Twist1 ubiquitination.
Naskar M et al. PLoS Pathog 2023; 19 (5):e1011388 α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification.
Z. Zhang et al. Genomics 2023; Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS)
Application : WB
Davies JP et al. bioRxiv 2023; SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response.
Bogucka-Janczi K et al. Elife 2023; 12 ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization.
Fusco P et al. Cell Biosci 2023; 13 (1):89 miR-210-3p enriched extracellular vesicles from hypoxic neuroblastoma cells stimulate migration and invasion of target cells.
Tseng YL et al. J Biomed Sci 2023; 30 (1):27 Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
RR Huang et al. JCTP 2023; Androgen Drives the Expression of SARS-CoV-2 Entry Proteins in Sinonasal Tissue
Application : WB
Reactivity : Human
Y Li et al. Cell Death Dis 2023; KLF12 promotes the proliferation of breast cancer cells by reducing the transcription of p21 in a p53-dependent and p53-independent manner
Application : WB
Reactivity : Human
Ghane MA et al. Front Cell Neurosci 2023; 17:1091324 Arc ubiquitination regulates endoplasmic reticulum-mediated Ca(2+) release and CaMKII signaling.
Application : WB
Feng XF et al. Front Cell Neurosci 2023; 17:1125412 Tetramethylpyrazine promotes stroke recovery by inducing the restoration of neurovascular unit and transformation of A1/A2 reactive astrocytes.
Application : WB
Reactivity : Rat
Xia K et al. Cell Death Dis 2023; 14 (4):250 Cryptochrome 2 acetylation attenuates its antiproliferative effect in breast cancer.
Application : WB
Reactivity : Human
Ferdous S et al. Front Cell Neurosci 2023; 17:1104592 Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure.
Application : WB
Reactivity : Mouse
Cheng H et al. Evid Based Complement Alternat Med 2023; 2023:8673136 Study on Neuroprotective Mechanism of Houshiheisan in Ischemic Stroke Based on Transcriptomics and Experimental Verification.
Application : WB
Reactivity : Rat
Arimoto KI et al. Nat Commun 2023; 14 (1):251 Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis.
Sych K et al. J Mol Med (Berl) 2023; 101 (1-2):151-169 Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro.
Tsui KH et al. Aging (Albany NY) 2023; 15 (1):246-260 Mitoquinone shifts energy metabolism to reduce ROS-induced oxeiptosis in female granulosa cells and mouse oocytes.
Jiang B et al. Mol Med Rep 2023; 27 (2) Combination of chloroquine diphosphate and salidroside induces human liver cell apoptosis via regulation of mitochondrial dysfunction and autophagy.
Shilts J et al. PLoS Biol 2023; 21 (2):e3001959 LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.
Application : WB
Reactivity : Human
Despic V et al. Nature 2023; 614 (7947):358-366 mRNA ageing shapes the Cap2 methylome in mammalian mRNA.
Application : WB
Reactivity : Human
Quiles JM et al. Sci Signal 2023; 16 (770):eabo4457 Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy.
Application : WB
Reactivity : Human
Binh DHN et al. Am J Cancer Res 2023; 13 (11):5151-5173 StAR-related lipid transfer domain protein 3 (STARD3) regulates HER2 and promotes HER2-positive breast cancer progression through interaction with HSP90 and SRC signaling.
Jahin I et al. Front Cell Dev Biol 2023; 11:1292775 Extracellular matrix stiffness activates mechanosensitive signals but limits breast cancer cell spheroid proliferation and invasion.
St-Denis-Bissonnette F et al. J Extracell Vesicles 2023; 12 (12):e12387 A clinically relevant large-scale biomanufacturing workflow to produce natural killer cells and natural killer cell-derived extracellular vesicles for cancer immunotherapy.
Hu CM et al. Adv Sci (Weinh) 2023; 10 (36):e2301240 Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for PanIN Initiation.
Escalante-Covarrubias Q et al. Nat Commun 2023; 14 (1):1685 Time-of-day defines NAD(+) efficacy to treat diet-induced metabolic disease by synchronizing the hepatic clock in mice.
Power AS et al. Circ Res 2023; 133 (12):1040-1055 Nitric Oxide Modulates Ca(2+) Leak and Arrhythmias via S-Nitrosylation of CaMKII.
Merchut-Maya JM et al. Cell Death Differ 2022; 29 (8):1639-1653 Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability.
Fernandez A et al. J Cell Sci 2022; 135 (6) Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress.
Application : WB
Reactivity : Human
Lopez-Toledo G et al. Front Aging Neurosci 2022; 14:921573 Patient-Derived Fibroblasts With Presenilin-1 Mutations, That Model Aspects of Alzheimer's Disease Pathology, Constitute a Potential Object for Early Diagnosis.
Application : WB
Reactivity : Human
Leitner N et al. Vet Res Commun 2022; 46 (4):1175-1193 Lipid droplets and perilipins in canine osteosarcoma. Investigations on tumor tissue, 2D and 3D cell culture models.
Application : WB
Reactivity : Dog
Usher JL et al. EMBO Rep 2022; 23 (12):e53552 Parkin drives pS65-Ub turnover independently of canonical autophagy in Drosophila.
Renaud E et al. Mol Cancer 2022; 21 (1):195 Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCδ for tumorigenesis.
Peters CE et al. Nat Commun 2022; 13 (1):5282 Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
Shebl B et al. JCI Insight 2022; 7 (17) Targeting BCL-XL in fibrolamellar hepatocellular carcinoma.
Guo L et al. Mol Cancer Ther 2022; 21 (5):740-750 Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 Inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells.
Application : WB
Reactivity : Human
Chadelle L et al. Cancer Lett 2022; 526:112-130 PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells.
Application : WB
Reactivity : Human
Huang CY et al. J Hepatocell Carcinoma 2022; 9:1385-1401 Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses.
Application : WB
Reactivity : Human
Yousefi M et al. PLoS Pathog 2022; 18 (8):e1010763 TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.
Application : WB
Reactivity : Human
Ferguson KM et al. Front Cell Dev Biol 2022; 10:983097 Lrig1 regulates the balance between proliferation and quiescence in glioblastoma stem cells.
Yeh CT et al. Biomedicines 2022; 10 (11) Immunoglobulin Y Specific for SARS-CoV-2 Spike Protein Subunits Effectively Neutralizes SARS-CoV-2 Infectivity and Ameliorates Disease Manifestations In Vivo.
Wu MH et al. Biomedicines 2022; 10 (10) Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In Vivo.
Wu CE et al. Am J Cancer Res 2022; 12 (9):4399-4410 In vitro and in vivo study of GSK2830371 and RG7388 combination in liver adenocarcinoma.
Ma S et al. PLoS One 2022; 17 (9):e0274618 Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction.
Guyard V et al. J Cell Biol 2022; 221 (9) ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER-mitochondria contact sites.
Zhang L et al. J Neuroendocrinol 2022; 34 (9):e13164 Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression.
Taura M et al. Proc Natl Acad Sci U S A 2022; 119 (20):e2011665119 APOBEC3A regulates transcription from interferon-stimulated response elements.
Revollo L et al. Blood 2022; 139 (1):104-117 The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation.
Yi-Ing Chen et al. Nat Commun 2022; 13 (1):2945 Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Application : WB
Reactivity : Human
Ashleigh Willis et al. Mol Neurobiol 2022; Enzymatic Degradation of Cortical Perineuronal Nets Reverses GABAergic Interneuron Maturation.
Application : WB
Reactivity : Mouse
Xue-Feng Feng et al. Front Pharmacol 2022; 13:851746 Magnetic Resonance Imaging Investigation of Neuroplasticity After Ischemic Stroke in Tetramethylpyrazine-Treated Rats.
Application : WB
Reactivity : Rat
Alexandra G Moyzis et al. Cells 2022; 11 (9) Mcl-1 Differentially Regulates Autophagy in Response to Changes in Energy Status and Mitochondrial Damage.
Application : WB
Yueh-Hua Chung et al. Sci Rep 2022; 12 (1):6955 MiR-26a-5p as a useful therapeutic target for upper tract urothelial carcinoma by regulating WNT5A/β-catenin signaling.
Application : WB
Reactivity : Human
Shwetha Shivaprasad et al. PLoS Pathog 2022; 18 (4):e1010163 Loquacious modulates flaviviral RNA replication in mosquito cells.
Application : WB
Yu-Hsuan Hung et al. Int J Mol Sci 2022; 23 (5) Semaphorin 6C Suppresses Proliferation of Pancreatic Cancer Cells via Inhibition of the AKT/GSK3/β-Catenin/Cyclin D1 Pathway.
Application : WB
Reactivity : Human, Mouse
Brigitte Potier et al. Int J Mol Sci 2022; 23 (2) DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus.
Application : WB
Reactivity : Mouse
Tram Anh Tran et al. J Biol Chem 2022; 298 (2):101515 Inhibition of Jumonji demethylases reprograms severe dilated cardiomyopathy and prolongs survival.
Application : WB
Reactivity : Mouse
Faqi Wang et al. Front Aging Neurosci 2022; 14:814560 Low-Intensity Focused Ultrasound Stimulation Ameliorates Working Memory Dysfunctions in Vascular Dementia Rats via Improving Neuronal Environment.
Application : WB
Reactivity : Rat
Hongmin Liang et al. Front Immunol 2022; 13:832458 Pyolysin of Trueperella pyogenes Induces Pyroptosis and IL-1β Release in Murine Macrophages Through Potassium/NLRP3/Caspase-1/Gasdermin D Pathway.
He L et al. EMBO Mol Med 2022;:e14990 CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.
Application : WB
Reactivity : Human
Wang LY et al. Int J Mol Sci 2022; 23 (5) The Anti-Proliferative and Apoptotic Effects of Rutaecarpine on Human Esophageal Squamous Cell Carcinoma Cell Line CE81T/VGH In Vitro and In Vivo.
Application : WB
Reactivity : Human
Magalh?es AC et al. Pathogens 2022; 11 (3) InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays.
Application : WB
Lai KC et al. J Cachexia Sarcopenia Muscle 2022; IFIT2-depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice.
Application : WB
Reactivity : Human
Dom?nguez-Sala E et al. Brain Struct Funct 2022; (Epub) Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction.
Application : WB
Reactivity : Mouse
Brettrager EJ et al. Sci Rep 2022; 12 (1):1625 Sulfotransferase 4A1 activity facilitates sulfate-dependent cellular protection to oxidative stress.
Application : WB
Reactivity : Yeast
Tracy TE et al. Cell 2022; 185 (4):712-728.e14 Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.
Application : WB
Reactivity : Human
Narayanan D et al. Virus Genes 2022; (Epub) Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment.
Oom AL et al. Mol Cell Proteomics 2022;:100194 Comparative Analysis of T Cell Spatial Proteomics and the Influence of HIV Expression.
Potier B et al. Int. J. Mol. Sci. 2022; 23 (2):592 DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus.
Application : WB
Reactivity : Mouse
Chien HM et al. Commun Chem 2021; 4 (1):111 Nanoscopic investigation of C9orf72 poly-GA oligomers on nuclear membrane disruption by a photoinducible platform.
Cheng TC et al. J Food Drug Anal 2021; 29 (4):622-637 Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein.
Application : WB
Reactivity : Human
Olivia Molinar-Inglis et al. Proc Natl Acad Sci U S A 2021; 118 (49) aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete, β-arrestin-2-mediated SphK1-S1PR1-Akt signaling axis.
Application : WB
Reactivity : Human
Karen Dunbar et al. Cell Mol Gastroenterol Hepatol 2021; 11 (2):465-489 Aspirin Rescues Wnt-Driven Stem-like Phenotype in Human Intestinal Organoids and Increases the Wnt Antagonist Dickkopf-1.
Application : WB
Reactivity : Human
Wen-Fang Tang et al. Biomed J 2021; 44 (3):293-303 Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.
Application : WB
Reactivity : Human
Ke Zhang et al. Sci Adv 2021; 7 (6) Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression.
Application : WB
Reactivity : Human
Jeanee Bullock et al. Invest Ophthalmol Vis Sci 2021; 62 (2):30 Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R).
Application : WB
Reactivity : Human
Katherine M Almasy et al. bioRxiv 2021; Comparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs.
Application : WB
Reactivity : Human
Gareth A Roberts et al. Nat Cell Biol 2021; 23 (8):834-845 Dissecting OCT4 defines the role of nucleosome binding in pluripotency.
Application : WB
Reactivity : Mouse
Yanqi Xie et al. Mol Cancer Ther 2021; 20 (10):1893-1903 Potent Synergistic Effect on C-Myc-Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor.
Application : WB
Reactivity : Human
Tung Chao et al. Autophagy 2021; 17 (11):3444-3460 Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability.
Application : WB
Reactivity : Human
Caini Fan et al. Int J Mol Sci 2021; 22 (8) NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium.
Application : WB
Reactivity : Human
Laura Martin-Sancho et al. Mol Cell 2021; Functional landscape of SARS-CoV-2 cellular restriction.
Application : WB
Reactivity : Human
Raul Bardini Bressan et al. Cell Stem Cell 2021; 28 (5):877-893.e9 Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants.
Application : WB
Reactivity : Human
Mar?a ?ngeles Marqu?s-Torrej?n et al. Nat Commun 2021; 12 (1):2594 LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Application : WB
Katherine M Almasy et al. Mol Cell Proteomics 2021;:100120 Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.
Application : WB
Chiao-En Wu et al. Cancers (Basel) 2021; 13 (15) WIP1 Inhibition by GSK2830371 Potentiates HDM201 through Enhanced p53 Phosphorylation and Activation in Liver Adenocarcinoma Cells.
Application : WB
Reactivity : Human
Zih-Yin Lai et al. Int J Mol Sci 2021; 22 (16) Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor.
Application : WB
Reactivity : Human
Shuyin Bao et al. Front Pharmacol 2021; 12:656220 Agriophyllum Oligosaccharides Ameliorate Diabetic Insulin Resistance Through INS-R/IRS/Glut4-Mediated Insulin Pathway in db/db Mice and MIN6 Cells.
Application : WB
Reactivity : Mouse
Nina-Naomi Kreis et al. Cells 2021; 10 (9) Functional Analysis of p21Cip1/CDKN1A and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia.
Application : WB
Reactivity : Human
Yueh-Ming Shyu et al. Int J Mol Sci 2021; 22 (18)
Application : WB
Reactivity : Human, Mouse
Antonino Asaro et al. J Cell Sci 2021; 134 (20) ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling.
Hong Xiang et al. MAbs 2021; 13 (1):1981202 Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer.
Application : WB
Reactivity : Human
Elena Porc? et al. iScience 2021; 24 (11):103350 The long non-coding RNA CDK6-AS1 overexpression impacts on acute myeloid leukemia differentiation and mitochondrial dynamics.
Application : WB
Wang LC et al. Front Aging Neurosci 2021; 13:741168 Somatosensory Cortical Electrical Stimulation After Reperfusion Attenuates Ischemia/Reperfusion Injury of Rat Brain.
Application : WB
Reactivity : Rat
Moon HH et al. Cancers (Basel) 2021; 13 (22) Mitotic Centromere-Associated Kinesin (MCAK/KIF2C) Regulates Cell Migration and Invasion by Modulating Microtubule Dynamics and Focal Adhesion Turnover.
Application : WB
Reactivity : Human
Garcia JD et al. Cell Rep 2021; 37 (12):110142 Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity.
Application : WB
Ren K et al. Virol J 2021; 18 (1):256 IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3.
Application : WB
De Sarkar N et al. JCI Insight 2021; 6 (23) Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.
Wang Y et al. Nature 2021; 599 (7883):136-140 SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.
Application : WB
Reactivity : Human
Mohseni YR et al. Eur J Immunol 2021; 51 (10):2522-2530 Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive.
Application : WB
Reactivity : Human
McCarthy GM et al. Dis Model Mech 2021; 14 (8) Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease.
Application : WB
Reactivity : Mouse
Yao CL et al. Aging (Albany NY) 2021; 13 (15):19878-19893 CCL2 associated with CD38 expression during ex vivo expansion in human cord blood-derived hematopoietic stem cells.
Application : WB
Reactivity : Human
Poobalasingam T et al. J Neurochem 2021; (Epub) The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons.
Application : WB
Reactivity : Human
Rada CC et al. Sci Signal 2021; 14 (698):eabc1044 Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption.
Application : WB
Reactivity : Human
Frydas A et al. Neurobiol Aging 2021; (Epub) Genetic variants in progranulin upstream open reading frames increase downstream protein expression.
Application : WB
Reactivity : Human
Yenerall P et al. Cancer Res 2021; 81 (18):4685-4695 Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.
Kwon J et al. Cell Mol Neurobiol 2021; (Epub) Differential Effects of Toll-Like Receptor Activation and Differential Mediation by MAP Kinases of Immune Responses in Microglial Cells.
Application : WB
Reactivity : Mouse
Chakraborty P et al. Nat Commun 2021; 12 (1):4126 DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination.
Application : WB
Reactivity : Human
Harley J et al. Brain Commun 2021; 3 (3):fcab166 TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain.
Application : WB
Reactivity : Human
Lin CC et al. Nat Commun 2021; 12 (1):3878 Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation.
Application : WB
Reactivity : Mouse
Lai Z.Y. et al. Int. J. Mol. Sci. 2021; 22 (16):8784 Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor.
Application : WB
Reactivity : Human
Lee TT et al. Aging Cell 2021; 20 (6):e13379 Loss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila.
Application : WB
Reactivity : Drosophila
Michelis G et al. J Neurochem 2021; Pigment epithelium-derived factor (PEDF) and derived peptides promote survival and differentiation of photoreceptors and induce neurite-outgrowth in amacrine neurons.
Application : WB
Reactivity : Pig
Maiques O et al. Br J Cancer 2021; A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma.
Application : WB
Reactivity : Mouse
?vila-Rosales OS et al. Toxics 2021; 9 (6) Daytime Restricted Feeding Modifies the Temporal Expression of CYP1A1 and Attenuated Damage Induced by Benzopmpyrene in Rat Liver When Administered before CYP1A1 Acrophase.
Application : WB
Reactivity : Rat
Shen CH et al. Front Cell Dev Biol 2021; 9:642625 ZNRF1 Mediates Epidermal Growth Factor Receptor Ubiquitination to Control Receptor Lysosomal Trafficking and Degradation.
Application : WB
Reactivity : Human
Park SH et al. PLoS Pathog 2021; 17 (5):e1009519 Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity.
Application : WB
Reactivity : Human
Chen XQ et al. Alzheimers Res Ther 2021; 13 (1):59 Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
Application : WB
Reactivity : Mouse
Baxley RM et al. Nat Commun 2021; 12 (1):1626 Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening.
Application : WB
Reactivity : Human
Sonnenberg SB et al. J Cell Sci 2021; 134 (4) The 5-HT4 receptor interacts with adhesion molecule L1 to modulate morphogenic signaling in neurons.
Application : WB
Reactivity : Human
Molinar-Inglis O. et al. bioRxiv 2021; (Epub) aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis.
Application : WB
Reactivity : Human
Deffieu MS et al. Sci Adv 2021; 7 (2) Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway.
Application : ICC/IF
Reactivity : Human
Wu J et al. J Biol Chem 2021;:100496 Arginine methylation of R81 in Smad6 confines BMP-induced Smad1 signaling.
Application : WB
Reactivity : Human
Arakaki AKS et al. J Cell Sci 2021; (Epub) α-arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis.
Application : WB
Biomedical Journal 2021; (Epub) Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation.
Application : WB
Reactivity : Monkey
Alexandra G Moyzis et al. J Mol Cell Cardiol 2020; 146:109-120 Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise.
Application : WB
Reactivity : Human
Prasad V Phatarpekar et al. J Cell Biol 2020; 219 (11) The septin cytoskeleton regulates natural killer cell lytic granule release.
Application : WB
Reactivity : Human
Daniel J Kim et al. J Virol 2020; 94 (22) RUNX Binding Sites Are Enriched in Herpesvirus Genomes, and RUNX1 Overexpression Leads to Herpes Simplex Virus 1 Suppression.
Application : WB
Reactivity : Human
Hueng-Chuen Fan et al. Int J Mol Sci 2020; 21 (22) Dehydroxyhispolon Methyl Ether, A Hispolon Derivative, Inhibits WNT/β-Catenin Signaling to Elicit Human Colorectal Carcinoma Cell Apoptosis.
Application : WB
Reactivity : Human
Tsong-Hai Lee et al. Cell Commun Signal 2020; 18 (1):185 The COX-2-derived PGE2 autocrine contributes to bradykinin-induced matrix metalloproteinase-9 expression and astrocytic migration via STAT3 signaling.
Application : WB
Reactivity : Rat
Zhentian Li et al. PLoS One 2020; 15 (11):e0235998 Replication stress and FOXM1 drive radiation induced genomic instability and cell transformation.
Application : WB
Reactivity : Human
Jonathan P Davies et al. ACS Infect Dis 2020; 6 (12):3174-3189 Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies.
Application : WB
Reactivity : Human
Soula M et al. Nat Chem Biol 2020; 16 (12):1351-1360 Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Lai PL et al. Oncol Lett 2020; 20 (3):2937-2945 Selection of a malignant subpopulation from a colorectal cancer cell line.
Agote-Aran A et al. EMBO J 2020; 39 (20):e104467 Spatial control of nucleoporin condensation by fragile X-related proteins.
Glaesel K et al. Int J Mol Sci 2020; 21 (11) miR-129-5p and miR-130a-3p Regulate VEGFR-2 Expression in Sensory and Motor Neurons during Development.
Hight SK et al. Neoplasia 2020; 22 (8):294-310 An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.
Chiang AJ et al. Biomolecules 2020; 11 (1) UBE2C Drives Human Cervical Cancer Progression and Is Positively Modulated by mTOR.
Application : WB
Reactivity : Human
McMichael BD et al. J Appl Toxicol 2020; (Epub) Long-term arsenic exposure impairs differentiation in mouse embryonal stem cells.
Application : WB
Reactivity : Mouse
Shin JE et al. Nutrients 2020; 12 (11) Soluble Whey Protein Hydrolysate Ameliorates Muscle Atrophy Induced by Immobilization via Regulating the PI3K/Akt Pathway in C57BL/6 Mice.
Application : WB
Reactivity : Mouse
Zhou X et al. Nat Commun 2020; 11 (1):6088 Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.
Application : WB
Reactivity : Mouse
Liu W et al. Oxid Med Cell Longev 2020; 2020:5167292 The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling.
Or CR et al. Int J Mol Sci 2020; 21 (5) Obatoclax, a Pan-BCL-2 Inhibitor, Downregulates Survivin to Induce Apoptosis in Human Colorectal Carcinoma Cells Via Suppressing WNT/β-catenin Signaling.
Chang-Ching Weng et al. Materials & Design 2020; 197:109230 Design and fabrication of cell-targeted, dual drug-loaded nanoparticles with pH-controlled drug release and near-infrared light-induced photothermal effects.
Application : WB
Reactivity : Human
Sarkar A et al. Mol Cell Biochem 2020; Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies.
Application : WB
Guarecuco R et al. Sci Adv 2020; 6 (41) Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells.
Application : WB
Reactivity : Human
Haupt M et al. Neuropharmacology 2020; 181:108357 Lithium enhances post-stroke blood-brain barrier integrity, activates the MAPK/ERK1/2 pathway and alters immune cell migration in mice.
Application : WB
Reactivity : Mouse
Schuster-Gaul S et al. JCI Insight 2020; 5 (2) ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Yun SI et al. Cancers (Basel) 2020; 12 (1) Ubiquitin-Specific Protease 21 Promotes Colorectal Cancer Metastasis by Acting as a Fra-1 Deubiquitinase.
Lee M et al. J Cell Biol 2020; 219 (2) Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.
Wang L et al. Proc Natl Acad Sci U S A 2020; 117 (1):563-572 A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes.
Nicholas DA et al. Sci Rep 2020; 10 (1):13063 GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes.
Application : WB
Reactivity : Mouse
Huang S et al. J Cell Mol Med 2020; 24 (19):11133-11145 Up-regulated acylglycerol kinase (AGK) expression associates with gastric cancer progression through the formation of a novel YAP1-AGK-positive loop.
Application : WB
Reactivity : Human
Young AM et al. Mol Biol Cell 2020; 31 (15):1551-1560 BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins.
Application : WB
Reactivity : Human
Qu Z et al. Biotechnol Lett 2020; 42 (12):2489-2500 Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway.
Application : WB
Reactivity : Drosophila
Rajgor D et al. Cell Rep 2020; 31 (12):107785 Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation.
Application : WB
Reactivity : Human
Liang W et al. Aging Cell 2020; 19 (8):e13187 Aging is associated with a decline in Atg9b-mediated autophagosome formation and appearance of enlarged mitochondria in the heart.
Application : WB
Reactivity : Mouse
Pennycook BR et al. Nat Commun 2020; 11 (1):3503 E2F-dependent transcription determines replication capacity and S phase length.
Application : WB
Reactivity : Human
Navarro-Mabarak C et al. Brain Res Bull 2020; 163:57-64 Neuroinflammation is able to downregulate cytochrome P450 epoxygenases 2J3 and 2C11 in the rat brain.
Application : WB
Reactivity : Rat
Gella A et al. Front Cell Dev Biol 2020; 8:660 Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.
Application : WB
Reactivity : Mouse
Sheets JN et al. Oncotarget 2020; 11 (24):2290-2301 SUSD2 expression correlates with decreased metastasis and increased survival in a high-grade serous ovarian cancer xenograft murine model.
Application : WB
Reactivity : Mouse
Bogucka K et al. Elife 2020; 9 ERK3/MAPK6 controls IL-8 production and chemotaxis.
Application : WB
Reactivity : Human
Chen PL et al. Nat Commun 2020; 11 (1):2592 Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster.
Application : WB
Reactivity : Drosophila
Yu TJ et al. Biomolecules 2020; 10 (5) Low Concentration of Withaferin a Inhibits Oxidative Stress-Mediated Migration and Invasion in Oral Cancer Cells.
Application : WB
Reactivity : Human
Duong P et al. Biol Sex Differ 2020; 11 (1):12 Neuroprotective and neurotoxic outcomes of androgens and estrogens in an oxidative stress environment.
Application : WB
Reactivity : Human
Bao S et al. J Ethnopharmacol 2020; 257:112863 Agriophyllum oligosaccharides ameliorate hepatic injury in type 2 diabetic db/db mice targeting INS-R/IRS-2/PI3K/AKT/PPAR-帠/Glut4 signal pathway.
Application : WB
Reactivity : Mouse
Valls-Lacalle L et al. Biomolecules 2020; 10 (4) Connexin 43 Deficiency Is Associated with Reduced Myocardial Scar Size and Attenuated TGF帣1 Signaling after Transient Coronary Occlusion in Conditional Knock-Out Mice.
Application : WB
Reactivity : Mouse
Bettina B?ttcher et al. Front Microbiol 2020; 11:794 The Transcription Factor Stp2 Is Important for Candida albicans Biofilm Establishment and Sustainability.
Application : WB
Reactivity : Candida albicans
Robertson R et al. Am J Pathol 2020; 190 (3):554-562 BAG3P215L/KO Mice as a Model of BAG3P209L Myofibrillar Myopathy.
Application : WB
Gasilina A et al. PLoS One 2020; 15 (3):e0229801 IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.
Application : WB
Reactivity : Human
Pedersen H et al. Int J Mol Sci 2020; 21 (5) Replication Protein A (RPA) Mediates Radio-Resistance of Glioblastoma Cancer Stem-Like Cells.
Application : WB
Reactivity : Human
Baltes F et al. Biochim Biophys Acta Mol Cell Res 2020; 1867 (5):118663 β1-Integrin binding to collagen type 1 transmits breast cancer cells into chemoresistance by activating ABC efflux transporters.
Application : WB
Reactivity : Human
Sarkar A et al. Haematologica 2020; (Epub) Ataxia telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Application : WB
Reactivity : Human
Dragan M et al. Cell Death Dis 2020; 11 (2):106 G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer.
Application : WB
Reactivity : Human
Wangta Liu et al. Oxidative Medicine and Cellular Longevity 2020; 2020:Article ID 5167292 The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling.
Application : WB
Reactivity : Human
Munshi A et al. Stem Cell Res Ther 2019; 10 (1):401 A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles.
Nguyen HD et al. Cancers (Basel) 2019; 11 (12) The α9 Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced PD-L1 Expression and Regulates Melanoma Cell Proliferation and Migration.
Jessen TN et al. Exp Cell Res 2019; 374 (1):128-139 VANGL2 protein stability is regulated by integrin αv and the extracellular matrix.
Li W et al. J Biol Chem 2019; 294 (15):5914-5922 Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells.
Tenkorang MAA et al. Endocrinology 2019; 160 (4):947-963 NADPH Oxidase Mediates Membrane Androgen Receptor-Induced Neurodegeneration.
Xia X et al. ACS Chem Biol 2019; 14 (5):994-1001 Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1.
Diep J et al. Nat Microbiol 2019; 4 (12):2523-2537 Enterovirus pathogenesis requires the host methyltransferase SETD3.
Wildner JM et al. Cells 2019; 8 (12) RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.
Bayraktar EC et al. Proc Natl Acad Sci U S A 2019; 116 (1):303-312 MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo.
Gama Sosa MA et al. Acta Neuropathol Commun 2019; 7 (1):6 Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.
Taura M et al. Proc Natl Acad Sci U S A 2019; 116 (6):2282-2289 Apobec3A maintains HIV-1 latency through recruitment of epigenetic silencing machinery to the long terminal repeat.
Nagano M et al. Commun Biol 2019; 2 (1):419 Rab5-mediated endosome formation is regulated at the trans-Golgi network.
Application : WB
Wantoch von Rekowski K et al. Biomolecules 2019; 9 (12)
Application : WB
Reactivity : Human
Galmozzi A et al. Nature 2019; 576 (7785):138-142 PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Application : WB
Botrugno OA et al. Haematologica 2019; (Epub) ATR addiction in multiple myeloma: synthetic lethal approaches exploiting established therapies.
Application : WB
Reactivity : Human
Majer O et al. Nature 2019; 575 (7782):371-374 Release from UNC93B1 reinforces the compartmentalized activation of select TLRs.
Application : WB
Reactivity : Human
Choquet K et al. J Biol Chem 2019; 294 (18):7445-7459 Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200.
Nagano M et al. Commun Biol 2019; 2:419 Rab5-mediated endosome formation is regulated at the trans-Golgi network.
Application : WB
Lin ST et al. Front Physiol 2019; 10:1308 Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells.
Application : WB
Reactivity : Mouse
Ritter A et al. Cells 2019; 8 (10) Subcutaneous and Visceral Adipose-Derived Mesenchymal Stem Cells: Commonality and Diversity.
Application : WB
Reactivity : Human
Schmidlin T et al. Cell Syst 2019; 9 (4):366-374.e5 High-Throughput Assessment of Kinome-wide Activation States.
Application : WB
Reactivity : Human
Ogola BO et al. Front Endocrinol (Lausanne) 2019; 10:586 G Protein-Coupled Estrogen Receptor Protects From Angiotensin II-Induced Increases in Pulse Pressure and Oxidative Stress.
Application : WB
Reactivity : Rat
Gatz C et al. Front Neurol 2019; 10:562 Identification of Cellular Pathogenicity Markers for SIL1 Mutations Linked to Marinesco-Sj?gren Syndrome.
Application : WB
Reactivity : Human
Vibhuti Vyas et al. FASEB 2019; (Epub) Adiponectin links maternal metabolism to uterine contractility.
Application : WB
Arantxa Agote-Ar?n et al. bioRxiv 2019; (Epub) Spatial control of nucleoporin assembly by Fragile X-related proteins.
Application : WB
Reactivity : Human
Hu Y et al. Mol Reprod Dev 2019; MiR-8-3p regulates hyperthermia-induced lactate secretion by targeting PPP2R5B in boar Sertoli cells.
Application : WB
Reactivity : Human
Majer O et al. Nature 2019; UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.
Application : WB
Akimoto Y et al. Am J Physiol Renal Physiol 2019; O-GlcNAcylation and Phosphorylation of β-Actin Serine199 in Diabetic Nephropathy.
Bolea I et al. Elife 2019; 8 Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome.
Application : WB
Reactivity : Mouse
Peiris MN et al. Haematologica 2019; (Epub) Oncogenic fusion protein BCR-FGFR1 requires BCR-mediated oligomerization and chaperonin Hsp90 for activation.
Application : WB
Reactivity : Human
YingGuo et al. CJD 2019; (Epub) MicroRNA-15a inhibits GLUT4 translocation and impairs glucose metabolism in L6 skeletal muscle via targeting of VAP-A.
Application : WB
Kreis NN et al. Cancers (Basel) 2019; 11 (7) Function of p21 (Cip1/Waf1/CDKN1A) in Migration and Invasion of Cancer and Trophoblastic Cells.
Application : WB
Reactivity : Human
Andreazza S et al. Nat Commun 2019; 10 (1):3280 Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila.
Application : WB
Reactivity : Drosophila
Fantini V et al. Cells 2019; 8 (8) Bioink Composition and Printing Parameters for 3D Modeling Neural Tissue.
Inserte J et al. J Mol Cell Cardiol 2019; 133:164-173 High-fat diet improves tolerance to myocardial ischemia by delaying normalization of intracellular PH at reperfusion.
Application : WB
Ham S et al. Mol Cells 2019; 42 (6):480-494 Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates.
Application : WB
Reactivity : Human
Cheng YP et al. Int J Mol Sci 2019; 20 (13) Blockade of STAT3 Signaling Contributes to Anticancer Effect of 5-Acetyloxy-6,7,8,4'-Tetra-Methoxyflavone, a Tangeretin Derivative, on Human Glioblastoma Multiforme Cells.
Application : WB
Reactivity : Human
Woodall BP et al. JCI Insight 2019; 5 Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice.
Application : WB
Berenice M?rquez-Valadez et al. Front. Neurosci. 2019; (Epub) The Systemic Administration of the Histamine H1 Receptor Antagonist/Inverse Agonist.
Application : WB
Reactivity : Rat
Lampert MA et al. Autophagy 2019; 15 (7):1182-1198 BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation.
Application : WB
Reactivity : Mouse
Goren I et al. Nitric Oxide 2019; 87:31-42 Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes.
Application : WB
Reactivity : Mouse
Chou CK et al. Environ Toxicol 2019; 34 (4):401-414 Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes.
Application : WB
Reactivity : Human
Bang BR et al. J Virol 2019; (Epub) Regulation of HCV infection by Cellular Retinoic Acid Binding Proteins through the modulation of lipid droplet abundance.
Application : WB
Reactivity : Human
Brifault C et al. Glia 2019; (Epub) LRP1 deficiency in microglia blocks neuro-inflammation in the spinal dorsal horn and neuropathic pain processing.
Application : WB
Reactivity : Mouse
Tseng HW et al. Cancers (Basel) 2019; 11 (2) * treatment suppresses melanoma cell growth and motility through modulation of microrna expression.
Application : WB
Reactivity : Human
Garcia-Bermudez J et al. Nature 2019; 567 (7746):118-122 Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death.
Application : WB
Reactivity : Human
Hu CM et al. Cell Metab 2019; (Epub) High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells.
Application : WB
Reactivity : Human
Takeuchi S et al. Am J Pathol 2019; 189 (2):391-404 Elevated Membrane Cholesterol Disrupts Lysosomal Degradation to Induce β-Amyloid Accumulation: The Potential Mechanism Underlying Augmentation of β-Amyloid Pathology by Type 2 Diabetes Mellitus.
Application : WB
Reactivity : Monkey
Arakaki AKS et al. J Biol Chem 2018; 293 (9):3350-3362 The α-arrestin ARRDC3 suppresses breast carcinoma invasion by regulating G protein-coupled receptor lysosomal sorting and signaling.
Le CT et al. PLoS One 2018; 13 (2):e0192146 LY2405319, an analog of fibroblast growth factor 21 ameliorates α-smooth muscle actin production through inhibition of the succinate-G-protein couple receptor 91 (GPR91) pathway in mice.
Sung K et al. J Neurosci 2018; 38 (14):3394-3413 Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception.
Chou CK et al. Int J Mol Sci 2018; 19 (7) Ethyl Acetate Extract of Scindapsus Cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells Through Modulating ER Stress.
Tripurani SK et al. Mol Biol Cell 2018; 29 (22):2784-2799 Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development.
Chen YL et al. Am J Cancer Res 2018; 8 (12):2548-2563 Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma.
Jakubzig B et al. Cancers (Basel) 2018; 10 (12) Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells-Deciphering Novel Potential Targets for a Cell Sensitization.
Application : WB
Ponert JM et al. Molecules 2018; 23 (10) Unfractionated and Low Molecular Weight * Reduce Platelet Induced Epithelial-Mesenchymal Transition in Pancreatic and Prostate Cancer Cells.
Application : WB
Reactivity : Human
Chakraborty P et al. Nat Commun 2018; 9 (1):4346 DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing.
Application : WB
Reactivity : Human
Erol C. Bayraktar et al. bioRxiv 2018; (Epub) MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo.
Application : WB
Reactivity : Mouse
Tiwari PM et al. Nat Commun 2018; 9 (1):3999 Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection.
Application : WB
Reactivity : Mouse
Rodrigues ACZ et al. Acta Physiol (Oxf) 2018;:e13195 The sympathetic nervous system regulates skeletal muscle motor innervation and acetylcholine receptor stability.
Application : WB
Reactivity : Mouse
Snyder B et al. Horm Behav 2018; 106:62-73 Androgens modulate chronic intermittent hypoxia effects on brain and behavior.
Application : WB
Reactivity : Rat
Baek JH et al. Am J Pathol 2018; (Epub) deletion of the mitochondrial complex-iv cofactor heme a/farnesyltransferase causes focal segmental glomerulosclerosis and * response.
Application : WB
Reactivity : Mouse
Ohta S et al. Mol Cell Proteomics 2018; (Epub) Quantitative proteomics of the mitotic chromosome scaffold reveals the association of BAZ1B with chromosomal axes.
Application : WB
Reactivity : Human
Olivia Majer et al. bioRxiv 2018; (Epub) Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity.
Application : WB
Olivia Majer et al. bioRxiv 2018; (Epub) An essential checkpoint for TLR9 signaling is release from 1 Unc93b1 in endosomes.
Application : WB
Grimsey NJ et al. Cell Rep 2018; 24 (12):3312-3323.e5 A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.
Application : WB
Reactivity : Human
Lai CY et al. J Neurosci 2018; 38 (43):9160-9174 Spinal RNF20-Mediated Histone H2B Monoubiquitylation Regulates mGluR5 Transcription for Neuropathic Allodynia.
Application : WB
Reactivity : Rat
Zhang Q et al. Oncol Rep 2018; (Epub) * improves adoptive carbonic anhydrase-ix-specific chimeric antigen receptor-modified nk92 cell therapy in mouse models of human renal cell carcinoma.
Takaichi Y et al. J Neuropathol Exp Neurol 2018; (Epub) Deposition of Phosphorylated α-Synuclein in the rTg4510 Mouse Model of Tauopathy.
Application : WB
Reactivity : Mouse
SHIJIE HE et al. bioRxiv 2018; (Epub) The tumor suppressor p53 promotes carcinoma invasion and collective cellular migration.
Application : WB
Reactivity : Human
Snuderl M et al. Nat Commun 2018; 9 (1):2868 Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.
Application : WB
Reactivity : Human
Ou Y et al. Int J Clin Exp Pathol 2018; 11 (6):3052-3060 Silencing profilin-1 confers protection from oxLDL injury in human vascular endothelial cells.
Application : WB
Reactivity : Human
Lu Y et al. Neural Regeneration Research 2018; 13 (7):1195-1203 Houshiheisan and its components promote axon regeneration after ischemic brain injury.
Application : WB
Reactivity : Rat
AshleighWillis et al. Journal of Neuroscience Methods 2018; (Epub) Distortion of protein analysis in primary neuronal cultures by serum albumin from culture medium: a methodological approach to improve target protein quantification.
Application : WB
Reactivity : Mouse
Kretschmer J et al. RNA 2018; (Epub) The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5'-3' exoribonuclease XRN1.
Application : WB
Reactivity : Human
Daniels LJ et al. Cardiovasc Diabetol 2018; 17 (1):89 Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats.
Application : WB
Reactivity : Rat
Chung YH et al. Lab Invest 2018; (Epub) BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling.
Application : WB
Reactivity : Mouse
Zhang N et al. J Cancer Sci Ther 2018; 10 (3) Separase Inhibitor Sepin-1 Inhibits Foxm1 Expression and Breast Cancer Cell Growth.
Application : WB
Reactivity : Human
Hayashi K et al. Sci Signal 2018; 11 (528) the interaction between ikkα and lc3 promotes type i * production through the tlr9-containing laposome.
Application : WB
Reactivity : Mouse
Miscianinov V. et al. Molecular Therapy 2018; (Epub) MicroRNA-148b targets the TGF-β pathway to regulate angiogenesis and endothelialto-mesenchymal transition during skin wound healing.
Application : WB
Reactivity : Human
Lee CH et al. Mol Cell 2018; 70 (3):435-448.e5 Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.
Application : WB
Reactivity : Mouse
Mrazkova B et al. Aging (Albany NY) 2018; 10 (3):434-462 Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence.
Application : WB
Reactivity : Human
Tanabe Y et al. Oncotarget 2018; 9 (18):14428-14443 IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.
Application : WB
Reactivity : Human
Tian L et al. Hindawi 2018; (Epub) Electroacupuncture at ST-36 protects interstitial cells of Cajal via sustaining heme oxygenase-1 positive M2 macrophages in the stomach of diabetic mice.
Application : WB
Reactivity : Mouse
Stefanovic-Barrett S et al. EMBO Rep 2018; (Epub) MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.
Application : WB
Reactivity : Human
Macdougall CE et al. Cell Metab 2018; 27 (3):588-601.e4 Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets.
Application : WB
Reactivity : Mouse
Gomez-Virgilio L et al. Mol Neurobiol 2018; (Epub) Soluble Factors from Human Olfactory Neural Stem/Progenitor Cells Influence the Fate Decisions of Hippocampal Neural Precursor Cells.
Application : WB
Reactivity : Human
Juneja M et al. J Neurol Neurosurg Psychiatry 2018; (Epub) PFN2 and GAMT as common molecular determinants of axonal Charcot-Marie-Tooth disease.
Application : WB
Reactivity : Mouse
Lan B et al. Am J Physiol Lung Cell Mol Physiol 2018; (Epub) Transient stretch induces cytoskeletal fluidization through the severing action of cofilin.
Application : WB
Reactivity : Human
Coppe A et al. Hum Mutat 2018; (Epub) Somatic mutations activating Wiskott-Aldrich syndrome protein concomitant with RAS pathway mutations in Juvenile myelomonocytic leukemia patients.
Application : WB
Schultz CR et al. Biochem J 2018; (Epub) Synergistic drug combination GC7/DFMO suppresses hypusine/spermidine-dependent eIF5A activation and induces apoptotic cell death in neuroblastoma.
Application : WB
Reactivity : Human
Nguyen G et al. Biochem Biophys Res Commun 2018; 495 (4):2649-2656 * ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and gpr91 inhibition.
Application : WB
Reactivity : Human, Mouse
Chang WT et al. Molecules 2017; 22 (5) A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression.
Hammoudi N et al. Cardiovasc Drugs Ther 2017; 31 (3):233-246 Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes.
Thompson EL et al. Nucleic Acids Res 2017; 45 (20):11837-11857 FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.
Gimpel P et al. Curr Biol 2017; 27 (19):2999-3009.e9 Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.
Lee YH et al. Oncol Lett 2017; 14 (1):171-179 DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells.
Application : WB
Reactivity : Human
Damiani E et al. Sci Rep 2017; 7:41959 Platelet activating factor-induced expression of p21 is correlated with histone acetylation.
Hammerling BC et al. Nat Commun 2017; 8:14050 A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance.
Zhang C et al. Mol Oncol 2017; 11 (3):280-294 TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.
Bressan RB et al. Development 2017; 144 (4):635-648 Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.
Lin YY et al. Mar Drugs 2017; 15 (1) Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis.
Yang PY et al. Oncotarget 2017; 8 (3):4196-4207 Andrographolide impedes cancer stemness and enhances radio-sensitivity in oral carcinomas via miR-218 activation.
Shentu TP et al. Sci Rep 2017; 7 (1):18052 Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation.
Application : WB
Reactivity : Human
Yamamoto W et al. J Cell Sci 2017; (Epub) Distinct roles for plasma membrane PtdIns(4)P and PtdIns(4,5)P2 during yeast receptor-mediated endocytosis.
Application : WB
Reactivity : Yeast
Kaehler M et al. Oncotarget 2017; 8 (54):92018-92031 MicroRNA-212/ABCG2-axis contributes to development of imatinib-resistance in leukemic cells.
Application : WB
Reactivity : Human
Newman EA et al. Cell Death Dis 2017; 8 (12):3208 Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation.
Application : WB
Reactivity : Human
Su WC et al. J Virol 2017; (Epub) Ubiquitination of the Cytoplasmic Domain of Influenza A Virus M2 Protein is Crucial for Production of Infectious Virus Particles.
Jessen TN et al. Exp Cell Res 2017; (Epub) VANGL2 interacts with integrin αv to regulate matrix metalloproteinase activity and cell adhesion to the extracellular matrix.
Application : WB
Reactivity : Human
Li F et al. Diabetologia 2017; (Epub) loss of renal snx5 results in impaired ide activity and * resistance in mice.
Application : WB
Reactivity : Human
Lee CH et al. bioRxiv 2017; (Epub) Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin.
Application : WB
Reactivity : Mouse
Lee CH et al. bioRxiv 2017; (Epub) Distinct stimulatory mechanisms regulate the catalytic activity of Polycomb Repressive Complex 2 (PRC2).
Application : WB
Reactivity : Mouse
Larhammar M et al. J Neurosci 2017; (Epub) The Ste20 family kinases MAP4K4, MINK1 and TNIK, converge to regulate stress induced JNK signaling in neurons.
Application : WB
Reactivity : Mouse
Brifault C et al. J Biol Chem 2017; (Epub) Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuro-inflammation.
Application : WB
Reactivity : Mouse
De Gasperi R et al. Sci Rep 2017; 7 (1):12888 Denervation-related alterations and biological activity of miRNAs contained in exosomes released by skeletal muscle fibers.
Application : WB
Reactivity : Mouse
Garza-Contreras J et al. eNeuro 2017; 4 (4) Presence of Androgen Receptor Variant in Neuronal Lipid Rafts.
Application : WB
Reactivity : Rat
Rong X et al. J Clin Invest 2017; (Epub) ER phospholipid composition modulates lipogenesis during feeding and in obesity.
Application : WB
Reactivity : Mouse
Tang B et al. Int J Cancer 2017; (Epub) microrna-324-5p regulates stemness, pathogenesis and sensitivity to * in multiple myeloma cells by targeting hedgehog signaling.
Application : WB
Reactivity : Human
Chung YH et al. Int J Mol Sci 2017; 18 (8) MiR-30a-5p Inhibits Epithelial-to-Mesenchymal Transition and Upregulates Expression of Tight Junction Protein Claudin-5 in Human Upper Tract Urothelial Carcinoma Cells.
Application : WB
Reactivity : Human
King HA et al. Sci Rep 2017; 7 (1):6542 Generation of ribosome imprinted polymers for sensitive detection of translational responses.
Application : WB
Reactivity : Human
Bouhy D et al. Acta Neuropathol 2017; (Epub) A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.
Application : WB
Reactivity : Mouse
Bartova M et al. Clin Exp Metastasis 2017; Expression of ezrin and moesin in primary breast carcinoma and matched lymph node metastases.
Application : WB
Reactivity : Human
Joly P et al. PLoS One 2017; 12 (6):e0179369 ERAD defects and the HFE-H63D variant are associated with increased risk of liver damages in Alpha 1-Antitrypsin Deficiency.
Application : WB
Reactivity : Human
Hammerling BC et al. Small GTPases 2017;:0 Isolation of Rab5-positive endosomes reveals a new mitochondrial degradation pathway utilized by BNIP3 and Parkin.
Application : WB
Reactivity : Mouse
Wang VY et al. Mol Cell 2017; Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity.
Application : WB
Reactivity : Mouse
Preusner M et al. Mol Cell 2017; Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals.
Application : WB
Reactivity : Mouse
Lee KH et al. Sci Rep 2017; 7 (1):4787 Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway.
Application : WB
Reactivity : Mouse
Pillay S et al. J Virol 2017; AAV serotypes have distinctive interactions with domains of the cellular receptor AAVR.
Application : WB
Reactivity : Human
Fang F et al. Sci Rep 2017; 7 (1):3868 Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease.
Application : WB
Reactivity : Mouse
Park JW et al. Mod Pathol 2017; (Epub) FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate.
Application : WB
Reactivity : Human
Zeng L et al. Biochem Pharmacol 2017; (Epub) MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation.
Application : WB
Reactivity : Human
Xiao X et al. Nucleic Acids Res 2017; (Epub) Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
Application : WB
Reactivity : Human
Wu JH et al. J Eur Acad Dermatol Venereol 2017; (Epub) Dysregulation of the MEK/ERK/MNK1 signaling cascade by middle T antigen of the trichoydsplasia spinulosa polyomavirus.
Application : WB
Reactivity : Human
Scherer SL et al. J Biol Chem 2017; (Epub) Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.
Application : WB
Reactivity : Mouse
Zhang J et al. J Biol Chem 2017; (Epub) Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.
Application : ICC/IF
Reactivity : Mouse
Guichard J et al. Am J Physiol Heart Circ Physiol 2017;:ajpheart.00027.2017 Desmin Loss and Mitochondrial Damage Precede Left Ventricular Systolic Failure in Volume Overload Heart Failure.
Application : WB
Reactivity : Rat
Dart AE et al. Oncogene 2017; (Epub) The drebrin/EB3 pathway drives invasive activity in prostate cancer.
Application : WB
Reactivity : Human
Fujiki K et al. J Biol Chem 2017; (Epub) Involvement of Notch1 signaling in malignant progression of A549 cells subjected to prolonged cadmium exposure.
Application : WB
Reactivity : Human
Respondek D et al. PLoS One 2017; 12 (3):e0173259 PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection.
Application : WB
Chen Y et al. Cell Signal 2017; 33:107-121 Casein Kinase 2 Interacting Protein-1 regulates * and M2 inflammatory macrophage polarization.
Delaney JR et al. Nat Commun 2017; 8:14423 Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.
Wang T et al. Cell 2017; (Epub) Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.
Application : WB
Reactivity : Human
Baba Y et al. Int J Mol Sci 2017; 18 (2) Deguelin Potentiates Apoptotic Activity of an EGFR Tyrosine Kinase Inhibitor (AG1478) in PIK3CA-Mutated Head and Neck Squamous Cell Carcinoma.
Application : WB
Reactivity : Human
Frasca D et al. Mech Ageing Dev 2017; (Epub) Obesity induces pro-inflammatory B cells and impairs B cell function in old mice.
Application : WB
Reactivity : Mouse
Huang WY et al. J Dermatol Sci 2017; (Epub) Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction.
Application : WB
Reactivity : Rat
Hutt DM et al. Methods Mol Biol 2017; 1510:77-91 Using Histone Deacetylase Inhibitors to Analyze the Relevance of HDACs for Translation.
Application : WB
Reactivity : Human
Chen-Jei Hong et al. PLoS Genet 2016; Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function
Application : WB
Reactivity : Mouse
Zhou W et al. Int J Mol Med 2016; 38 (5):1481-1489 Expression of glycine receptors and gephyrin in rat medial vestibular nuclei and flocculi following unilateral labyrinthectomy.
Gan Z et al. Cell Syst 2016; 3 (3):252-263.e8 Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration.
Application : WB
Reactivity : Human
Zhang D et al. Oncotarget 2016; 7 (43):69149-69158 Targeting the ERK pathway for the treatment of Cushing's disease.
Application : WB
Reactivity : Mouse
Ahmad F et al. Sci Rep 2016; 6:28056 Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.
Application : WB
Reactivity : Mouse
Xiao X et al. Nat Commun 2016; 7:12193 Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Application : WB
Reactivity : Human
Jiang P et al. Oncotarget 2016; 7 (36):57932-57942 Anti-cancer effects of nitrogen-containing bisphosphonates on human cancer cells.
Application : WB
Reactivity : Human
Starokadomskyy P et al. Nat Immunol 2016; 17 (5):495-504 dna polymerase-α regulates the activation of type i *s through cytosolic rna:dna synthesis.
Application : WB
Reactivity : Human
Paudyal A et al. J Physiol 2016; 594 (12):3287-305 Nuclear accumulation of myocyte muscle LIM protein is regulated by heme oxygenase 1 and correlates with cardiac function in the transition to failure.
Application : WB
Reactivity : Pig
Chang WT et al. Anticancer Agents Med Chem 2016; (Epub) 9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1,2-c]quinolin-11-one (BPIQ), a quinoline derivative inhibits human hepatocellular carcinoma cells by inducing ER stress and apoptosis.
Application : WB
Reactivity : Human
Schultz AS et al. Mol Cell Biol 2016; (Epub) Activation-dependent TRAF3 exon 8 alternative splicing is controlled by CELF2 and hnRNP C binding to an upstream intronic element.
Application : WB
Reactivity : Human
Yang HH et al. Proteomics Clin Appl 2016; (Epub) the putative involvement of actin binding proteins and cytoskeleton proteins in pathological mechanisms of * cystitis - revealed by a prospective pilot study using proteomic approaches.
Application : WB
Reactivity : Human
Chroma K et al. Oncogene 2016; (Epub) Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress.
Application : WB
Reactivity : Human
Martinez-Castillo M et al. PLoS One 2016; 11 (11):e0165971 A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe.
Application : WB
Reactivity : Human
Korinek M et al. Phytomedicine 2016; 23 (14):1706-1715 Anti-allergic potential of Typhonium blumei: Inhibition of degranulation via suppression of PI3K/PLCγ2 phosphorylation and calcium influx.
Edmonds S et al. ACS Nano 2016; (Epub) Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines.
Application : WB
Reactivity : Mouse
Sheets JN et al. Oncogenesis 2016; 5 (10):e264 SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance.
Application : WB
Reactivity : Human
Zhou W et al. Int J Mol Med 2016; 38:1481-1489 Expression of glycine receptors and gephyrin in rat medial vestibular nuclei and flocculi following unilateral labyrinthectomy.
Application : WB
Reactivity : Rat
Kuga T et al. Sci Rep 2016; 6:34472 Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON.
Wu JH et al. J Med Virol 2016; Molecular mechanisms supporting a pathogenic role for human polyomavirus 6 small T antigen: Protein phosphatase 2A targeting and MAPK cascade activation.
Application : WB
Reactivity : Human
Aryal B et al. Nat Commun 2016; 7:12313 ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Application : WB
Reactivity : Mouse
Tsai WT et al. J Biol Chem 2016; 291 (37):19299-311 Mycotoxin Patulin Suppresses Innate Immune Responses by Mitochondrial Dysfunction and p62/Sequestosome-1-dependent Mitophagy.
Application : WB
Reactivity : Mouse
Steven S et al. Br J Pharmacol 2016;
Application : WB
Reactivity : Human
Wilhelmi I et al. Nat Commun 2016; 7:12347 Sec16 alternative splicing dynamically controls COPII transport efficiency.
Application : WB
Reactivity : Human
Smith TH et al. J Biol Chem 2016; (Epub) Protease-activated Receptor-4 Signaling and Trafficking Is Regulated by the Clathrin Adaptor Protein Complex-2 Independent of β-arrestins.
Application : WB
Reactivity : Human
Hahm ER et al. Cell Cycle 2016;:43112 c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells.
Application : WB
Reactivity : Human
Tsai KW et al. Sci Rep 2016; 6:28176 Arm Selection Preference of MicroRNA-193a Varies in Breast Cancer.
Application : WB
Reactivity : Human
Yu T et al. Cell Death Dis 2016; 7 (6):e2255 KLF4 deletion alters gastric cell lineage and induces MUC2 expression.
Application : WB
Reactivity : Human
Mankouri J et al. J Virol 2016; (Epub) Release of infectious hepatitis C virus from Huh7 cells occurs via a trans-Golgi network to endosome pathway independent of VLDL.
Application : WB
Reactivity : Human
Kuga T et al. Sci Rep 2016; 6:26557 FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes.
Application : WB
Reactivity : Human
Toste PA et al. Mol Cancer Res 2016; 14 (5):437-47 Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK.
Application : WB
Reactivity : Human
Delphine B. et al. JND 2016; Preprint:43118 Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.
Pacold ME et al. Nat Chem Biol 2016; 12 (6):452-8 A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.
Li YH et al. J Biol Chem 2016; 291 (19):10277-92 Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.
Application : WB
Reactivity : Human
Lisa J. Bain et al. Toxicol Rep 2016; 3:405-413 Arsenic inhibits stem cell differentiation by altering the interplay between the Wnt3a and Notch signaling pathways.
Application : WB
Reactivity : Mouse
Moreno-Lorenzana D et al. Cell Cycle 2016; (Epub):0 CDKIs p18INK4c and p57Kip2 are involved in quiescence of CML leukemic stem cells after treatment with TKI.
Application : WB
Reactivity : Human
Rowe ER et al. J Biol Chem 2016; 291 (13):6664-78 Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1-3.
Application : WB
Reactivity : Yeast, Monkey
Pillay S et al. Nature 2016; ([Epub ahead of print]) An essential receptor for adeno-associated virus infection.
Application : WB
Reactivity : Human
Egerman MA et al. Cell Metab 2015; 22 (1):164-74 GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.
Application : WB
Reactivity : Mouse
Ma F et al. J Immunol 2015; 194 (4):1545-54 Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.
Application : WB
Reactivity : Mouse
Tian H et al. Mol Cancer Res 2015; 13 (4):784-94 Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.
Application : WB
Reactivity : Human
Kelley RA et al. J Biol Chem 2015; 290 (8):5041-52 Retbindin is an extracellular riboflavin-binding protein found at the photoreceptor/retinal pigment epithelium interface.
Application : WB
Reactivity : Mouse
Zhang X et al. Clin Cancer Res 2015; 21 (20):4698-708 SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer.
Application : WB
Reactivity : Human
Huang TT et al. Oncotarget 2015; 6 (20):18012-26 The reciprocal regulation loop of Notch2 pathway and miR-23b in controlling gastric carcinogenesis.
Application : WB
Reactivity : Human
Zengel J et al. J Virol 2015; 89 (14):7338-47 Roles of Phosphorylation of the Nucleocapsid Protein of Mumps Virus in Regulating Viral RNA Transcription and Replication.
Application : WB
Reactivity : Monkey
Jo A et al. Biomed Res Int 2015; 2015:305716 Efficient Mitochondrial Genome Editing by CRISPR/Cas9.
Application : WB
Reactivity : Human
Grimsey NJ et al. J Cell Biol 2015; 210 (7):1117-31 Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes.
Application : WB
Reactivity : Human
Lin TB et al. J Neurosci 2015; 35 (50):16545-60 Fbxo3-Dependent Fbxl2 Ubiquitination Mediates Neuropathic Allodynia through the TRAF2/TNIK/GluR1 Cascade.
Application : WB
Reactivity : Rat
Wu JC et al. Sci Rep 2015; 5:18476 Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration.
Application : WB
Reactivity : Human
Shi J et al. Mol Cell Biol 2015; 35 (19):512011 Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling.
Kohl S et al. Nat Genet 2015; 47 (7):757-65 Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.
Paret C et al. Oncotarget 2015; 6 (28):25356-67 CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer.
Jacinto FV et al. Genes Dev 2015; 29 (12):1224-38 The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing.
Huber RM et al. Oncotarget 2015; 6 (4):2134-47 DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance.
Wei-Chou Lin et al. Am J Cancer Res 2015; 5 (11):3350-3362 mln4924, a novel nedd8-activating enzyme inhibitor, exhibits antitumor activity and enhances *-induced cytotoxicity in human cervical carcinoma: in vitro and in vivo study.
Application : WB
Reactivity : Human
Chou CK et al. Int J Mol Sci 2015; 16 (7):15104-17 BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9.
Application : WB
Reactivity : Human
Kubli DA et al. PLoS One 2015; 10 (6):e0130707 PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes.
Application : WB
Reactivity : Mouse
Virts EL et al. Hum Mol Genet 2015; 24 (18):5093-108 AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.
Application : WB
Reactivity : Human
Fu H et al. Nat Commun 2015; 6:6746 The DNA repair endonuclease Mus81 facilitates fast DNA replication in the absence of exogenous damage.
Application : WB
Reactivity : Human
Yu HW et al. J Cell Mol Med 2015; 19 (5):934-47 β-PIX controls intracellular viscoelasticity to regulate lung cancer cell migration.
Application : WB
Reactivity : Human
Yang M et al. J Lipid Res 2014; 55 (2):226-38 Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake.
Application : EMSA
Reactivity : Human
Corradini E et al. Mol Cell Proteomics 2014; 13 (8):2004-16 Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse.
Application : WB
Reactivity : Mouse
Fragkouli A et al. Front Cell Neurosci 2014; 8:182 miR-7 and miR-153 protect neurons against MPP(+)-induced cell death via upregulation of mTOR pathway.
Application : WB
Reactivity : Mouse
Jullienne A et al. J Cereb Blood Flow Metab 2014; 34 (10):1637-45 Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation.
Application : WB
Reactivity : Rat
Hutt DM et al. PLoS One 2014; 9 (8):e106224 The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition.
Application : WB
Reactivity : Human
Yang SH et al. Biomed Res Int 2014; 2014:312847 Andrographolide induces apoptosis of C6 glioma cells via the ERK-p53-caspase 7-PARP pathway.
Application : WB
Reactivity : Rat
Ma F et al. Nat Commun 2014; 5:5494 retinoid x receptor α attenuates host antiviral response by suppressing type i *.
Application : WB
Reactivity : Mouse
Chaudhury I et al. Mol Cell Biol 2014; 34 (21):3939-54 FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.
Yeo JE et al. Hum Mol Genet 2014; 23 (14):3695-705 CtIP mediates replication fork recovery in a FANCD2-regulated manner.
Huang IH et al. J Cell Sci. 2014; 127 (Pt 19):4186-200 GEF-H1 controls focal adhesion signaling that regulates mesenchymal stem cell lineage commitment.
Application : WB
Reactivity : Human
Kang CC et al. Anal Chem 2014; 86 (20):10429-36 Single-cell Western blotting after whole-cell imaging to assess cancer chemotherapeutic response.
Application : WB
Reactivity : Human
Dvoriantchikova G et al. Eur J Neurosci 2014; Tumor necrosis factor-alpha mediates activation of NF-κB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways.
Application : WB
Reactivity : Mouse
Lin CH et al. Int Immunopharmacol 2014; The effect of sesamin on airway fibrosis in vitro and in vivo.
Application : WB
Reactivity : Human, Mouse
James AW et al. Tissue Eng Part A 2014; Lentiviral delivery of PPARγ shRNA Alters the Balance of Osteogenesis and Adipogenesis, Improving Bone Microarchitecture.
Application : WB
Reactivity : Mouse
Kohsaka S et al. Nat Genet 2014; 46 (6):595-600 A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations.
Application : WB
Reactivity : Human
Grabiner BC et al. Cancer Discov 2014; A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity.
Application : WB
Reactivity : Human
Johnson MA et al. PLoS One 2014; 9 (4):e93597 Amino Acid starvation has opposite effects on mitochondrial and cytosolic protein synthesis.
Application : WB
Reactivity : Human
Colbert LE et al. Cancer Res 2014; CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer.
Application : WB
Reactivity : Human
Al-Sawaf O et al. Sci Rep 2014; 4:3625 Nrf2 protects against TWEAK-mediated skeletal muscle wasting.
Application : WB
Reactivity : Mouse
Morcavallo A et al. Matrix Biol 2014; decorin differentially modulates the activity of * receptor isoform a ligands.
Application : WB
Liu SH et al. Biochem Pharmacol 2014; 87 (2):229-42 Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy.
Application : WB
Reactivity : Human
Lin W et al. EMBO J 2013; 32 (10):1425-39 Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity.
Application : WB
Reactivity : Human
Ruisu K et al. PLoS One 2013; 8 (8):e74031 Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death.
Application : WB
Reactivity : Mouse
Chang YC et al. EMBO Mol Med 2013; 5 (8):1165-79 Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human.
Application : WB
Reactivity : Mouse
Lam T et al. PLoS One 2013; 8 (11):e80414 Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
Application : WB
Reactivity : Human
Zhang K et al. J Neurosci 2013; 33 (17):7451-62 Defective axonal transport of Rab7 GTPase results in dysregulated trophic signaling.
Application : WB
Reactivity : Rat
Son J et al. Genes Dev 2013; 27 (24):2663-77 Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.
Application : WB
Reactivity : Mouse
Angulo-Rojo C et al. ASN Neuro 2013; 5 (5):e00130 Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA.
Application : WB
Reactivity : Rat
Hall WA et al. Oncogene 2013; Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.
Application : WB
Reactivity : Human
Krieger M et al. Brain 2013; 136 (Pt 12):3634-44 SIL1 mutations and clinical spectrum in patients with Marinesco-Sjogren syndrome.
Application : WB
Reactivity : Human
Cho YW et al. PLoS One 2013; 8 (6):e66514 Zfp423 binds autoregulatory sites in p19 cell culture model.
Application : WB
Reactivity : Human
Chaudhury I et al. Nucleic Acids Res 2013; 41 (13):6444-59 FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery.
Application : WB
Reactivity : Human
Bennett BJ et al. Cell Metab 2013; 17 (1):49-60 Trimethylamine-N-oxide, a * associated with atherosclerosis, exhibits complex genetic and dietary regulation.
Application : WB
Reactivity : Mouse
Yang Y et al. Nucleic Acids Res 2013; 41 (4):2296-312 Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage.
Application : WB
Reactivity : Human
Sun Y et al. J Biol Chem 2012; 287 (48):40652-60 Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy.
Lim ST et al. J Cell Biol 2012; 197 (7):907-19 Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression.
Application : WB
Reactivity : Mouse
Clone Reference
S?nchez-Ram?rez E et al. J Cell Biol 2022; 221 (12) Coordinated metabolic transitions and gene expression by NAD+ during adipogenesis.
Natascha Leitner et al. BMC Vet Res 2022; 18 (1):221 Lipid droplet dynamics in healthy and pyometra-affected canine endometrium.
Application : WB
Reactivity : Dog
Antonino Asaro et al. J Cell Sci 2021; 134 (20) ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling.
Application : WB
Reactivity : Mouse, Hamster
Revollo L. et al. bioRxiv 2021; (Epub) The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation.
Klatt D et al. Cells 2020; 9 (10) Competitive sgRNA Screen Identifies p38 MAPK as a Druggable Target to Improve HSPC Engraftment.
Tran DT et al. Diabetes 2020; 69 (8):1723-1734 Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.
Lu RA et al. Front Pharmacol 2020; 11:469 Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins.
Alex G. Johnson et al. bioRxiv 2019; (Epub) A memory of RPS25 loss drives resistance phenotypes.
Ma S et al. Am J Physiol Renal Physiol 2019; 317 (3):F623-F631 Knockout of TRPA1 exacerbates angiotensin II-induced kidney injury.
Olabisi OA et al. Proc Natl Acad Sci U S A 2016; 113 (4):830-7 APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.
Schrecengost RS et al. Mol Cancer Res 2015; 13 (12):1591-601 Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression.
Heneghan JF et al. Am J Physiol Cell Physiol 2015; 309 (5):C332-47 BH3 domain-independent apolipoprotein L1 toxicity rescued by BCL2 prosurvival proteins.
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