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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.

  • Specification

    Product Description

    GREM2 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human GREM2 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

    Suitable Sample

    Cell culture supernates, cell lysates, serum and plasma (heparin, EDTA)

    Sample Volume

    100 uL

    Label

    HRP-conjugated

    Detection Method

    Colorimetric

    Assay Type

    Quantitative

    Calibration Range

    62.5 to 4000 pg/mL

    Reactivity

    Human

    Regulatory Status

    For research use only (RUO)

    Quality Control Testing

    Standard curve

    The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.

    Storage Instruction

    Store at 4°C for six months. For long term storage store at -20°C.
    Avoid repeated freezing and thawing.

  • Applications

    Quantification

  • Gene Info — GREM2

    Entrez GeneID

    64388

    Gene Name

    GREM2

    Gene Alias

    CKTSF1B2, DAND3, PRDC

    Gene Description

    gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)

    Omim ID

    608832

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq

    Other Designations

    OTTHUMP00000037834|cysteine knot superfamily 1, BMP antagonist 2|gremlin 2|protein related to DAN and cerberus

  • Interactome
  • Disease