General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.062ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This DHCR7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | DHCR7 |
| Gene ID: | 1717 |
| Uniprot ID: | DHCR7_HUMAN |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Widely expressed. Most abundant in adrenal gland, liver, testis, and brain. |
| Post Translational Modifications | |
| Function | 7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway. |
| Protein Name | 7-Dehydrocholesterol Reductase7-Dhc ReductaseDelta7-Sterol ReductaseSterol Delta(7-ReductaseSterol Reductase Sr-2 |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-6807047Reactome: R-HSA-6807062 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | 7-Dehydrocholesterol Reductase ELISA kit7-Dhc Reductase ELISA kitDelta7-Sterol Reductase ELISA kitSterol Delta(7-Reductase ELISA kitSterol Reductase Sr-2 ELISA kitDHCR7 ELISA kitD7SR ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance