General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.063ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This P2RY12 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | P2RY12 |
| Gene ID: | 64805 |
| Uniprot ID: | P2Y12_HUMAN |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Description
| Tissue Specificity | Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain. |
| Post Translational Modifications | |
| Function | Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. |
| Protein Name | P2y Purinoceptor 12P2y12Adp-Glucose ReceptorAdpg-RP2t(AcP2y(AcP2y(CycP2y12 Platelet Adp ReceptorP2y(AdpSp1999 |
| Database Links | Reactome: R-HSA-392170Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | P2y Purinoceptor 12 ELISA kitP2y12 ELISA kitAdp-Glucose Receptor ELISA kitAdpg-R ELISA kitP2t(Ac ELISA kitP2y(Ac ELISA kitP2y(Cyc ELISA kitP2y12 Platelet Adp Receptor ELISA kitP2y(Adp ELISA kitSp1999 ELISA kitP2RY12 ELISA kitHORK3 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance