Human SCAMP5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SCAMP5
Locus ID	192683
Kit Components	GA116257G1, SCAMP5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116257G2, SCAMP5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116257G3, SCAMP5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001178111, NM_001178112, NM_138967, NR_033660
UniProt ID	Q8TAC9
Synonyms	DKFZp686L1799; MGC24969
Summary	Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway.[UniProtKB/Swiss-Prot Function]