Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hydroxychloroquine [118-42-3]
Cat# T9287-200mg
Size : 200mg
Brand : TargetMol
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Hydroxychloroquine
Catalog No. T9287 CAS 118-42-3
Synonyms: 2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol
Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19.
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Hydroxychloroquine, CAS 118-42-3
| Description | Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It is a medication used to prevent and treat malaria, and it's also being studied as an experimental treatment for COVID-19. |
| Synonyms | 2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol |
| Molecular Weight | 335.87 |
| Formula | C18H26ClN3O |
| CAS No. | 118-42-3 |
Storage
Solubility Information
H2O: 1.65 mg/mL (4.91 mM), Sonification and heating to 60℃ are recommended.
DMSO: < 1 mg/mL (insoluble or slightly soluble)
1M HCl: 99 mg/mL (294.75 mM), when pH is adjusted to 2 with HCl.
Citations
1. Nicholson M W, Huang C Y, Wang J Y, et al. Cardio-and Neurotoxicity of Selected Anti-COVID-19 Drugs. Pharmaceuticals. 2022, 15(6): 765 2. Wang Z, Tan M, Su W, et al.Persistent Degradation of HER2 Protein by Hybrid nanoPROTAC for Programmed Cell Death.Journal of Medicinal Chemistry.2023