MMP-14 Colorimetric Cell-Based ELISA Kit
Cat# OKAG00883
Size : One96-WellPlate
Brand : Aviva Systems Biology
MMP-14 Colorimetric Cell-Based ELISA Kit (OKAG00883)
| Datasheets/Manuals | Printable datasheet for MMP-14 Colorimetric Cell-Based ELISA Kit (OKAG00883) |
|---|
| Predicted Species Reactivity | Homo sapiens|Human|Mouse|Rat |
|---|---|
| Product Format | 96-Well Microplate |
| Application | ELISA |
| ELISA Kit Detection Method | Colorimetric 450 nm |
| ELISA Kit Duration | 4.5 hours |
| ELISA Kit Range | At least 5000 cells/well |
| Additional Information | Dynamic Range: > 5000 Cells |
| :: | OMIM: 600754 UniGene: Hs.2399 |
| :: | Note: The product is for research use only, not for use in diagnostic or therapeutic procedures. |
| Reconstitution and Storage | 2°C to 8°C |
| Assay Info | Assay Type: Cell-Based Subtype: None Detection Method: Colorimetric 450 nm |
| Gene Symbol | MMP14 |
|---|---|
| Gene Full Name | matrix metallopeptidase 14 |
| Alias Symbols | matrix metallopeptidase 14 (membrane-inserted), matrix metalloproteinase-14, membrane type 1 metalloprotease, Membrane-type matrix metalloproteinase 1, membrane-type-1 matrix metalloproteinase, MMP-14, MMP-X1, MT-MMP, MT-MMP 1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS. |
| NCBI Gene Id | 4323 |
| Protein Name | Matrix metalloproteinase-14 |
| Description of Target | Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140). |
| Uniprot ID | P50281 |
