General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 2.0ng/mL |
| Detection Limit: | 4.68-300ng/mL |
| Short Description: | This IGFBP3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
Information
| Gene Symbol: | Igfbp3 |
| Gene ID: | 16009 |
| Uniprot ID: | IBP3_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | serum, plasma or other biological fluids. |
Description
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Promotes testicular germ cell apoptosis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 3Ibp-3Igf-Binding Protein 3Igfbp-3 |
| Database Links | Reactome: R-MMU-381426Reactome: -MMU-6803211Reactome: -MMU-8957275 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Insulin-Like Growth Factor-Binding Protein 3 ELISA kitIbp-3 ELISA kitIgf-Binding Protein 3 ELISA kitIgfbp-3 ELISA kitIgfbp3 ELISA kitIgfbp-3 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance