Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Glycolylneuraminic acid [1113-83-3]
Cat# T19456-50mg
Size : 50mg
Brand : TargetMol
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N-Glycolylneuraminic acid
Catalog No. T19456 CAS 1113-83-3
Synonyms: NeuGc, GcNeu
N-Glycolylneuraminic acid (GcNeu) is a nonhuman sialic acid molecule synthesized in pigs. N-Glycolylneuraminic acid is a receptor of human and animal IAVs.
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N-Glycolylneuraminic acid, CAS 1113-83-3
| Description | N-Glycolylneuraminic acid (GcNeu) is a nonhuman sialic acid molecule synthesized in pigs. N-Glycolylneuraminic acid is a receptor of human and animal IAVs. |
| In vitro | Expression of N-Glycolylneuraminic acid on human cells clearly suppressed infectivity of IAVs that possess N-Glycolylneuraminic acid binding ability. Furthermore, there was no difference in infectivity of a transfectant virus that included the wild-type HA gene from A/Memphis/1/1971 (H3N2), which shows no N-Glycolylneuraminic acid binding, between parent MCF7 cells and cells stably expressing the monkey CMAH gene (CMAH-MCF7 cells). On the other hand, cell entry of the transfectant virus that included the N-Glycolylneuraminic acid-binding HA gene with a single mutation to Tyr at position Thr155 was arrested at the stage of internalization from the plasma membrane of the CMAH-MCF7 cells[1]. |
| Synonyms | NeuGc, GcNeu |
| Molecular Weight | 325.27 |
| Formula | C11H19NO10 |
| CAS No. | 1113-83-3 |
Storage
Solubility Information
DMSO: 76 mg/mL (233.65 mM)
References and Literature