300124 | TNF-alpha peptide Clinisciences

Blocking Peptide

Synthetic Peptide

Cat. No.

300124

Unit

0.1 mg

Description

Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection.

Spec Container

Datasheet

Format

Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

Alternate Names

Tumor necrosis factor; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; TNF; TNFA; TNFSF2

Accession No.

P01375

3832.5 g/mol

Sequence

The synthetic peptide used to raise the antibody Cat. No. 251900 is selected from a sequence within the C-term region of human TNF-alpha. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Composition

C171H264N44O54S1

Purity

Purity > 80% by HPLC

Solubility

Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage

Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.

Related Products

Peptide Products
Product Name	Applications	SKU
2B-(A) Peptide		350453
2B-(S) Peptide		350454
A-779 Peptide		350455
ABCB6 Peptide		300116
Ac-DE Peptide		350457
Ac-SDKP Peptide		350461
Acetyl Alpha-Endorphin Peptide		350458
ACTH [1-10] Peptide		350018
ACTH [1-13] Peptide		350019
ACTH [1-14] Peptide		350020
ACTH [1-16] Peptide		350021
ACTH [1-17] Peptide		350022
ACTH [1-24] Peptide		350023
ACTH [1-39] Peptide		350024
ACTH [1-39] Peptide (Rat)		350025
ACTH [1-4] Peptide		350026
ACTH [18-39] Peptide		350027
ACTH [4-10] Peptide		350028

Antibody Products
Product Name	Applications	SKU
ACEI Antibody	E, IHC, WB	250451
ADAM-TS2 Antibody	E, IHC, WB	251979

For research use only, not for diagnostic or therapeutic procedures.

TNF-alpha peptide

Cat# 300124

Brand : Abbiotec

Spec Container

You might also be interested by the following products: