Reagents and instruments for immunology, cell biology and molecular biology.

Tributyrin [60-01-5]

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Cat# T19676-5mL

Size : 5mL

Brand : TargetMol

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Tributyrin

(Synonyms: NSC-661583, NSC661583, NSC 661583) Copy Product Info

Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.

Cas No. 60-01-5

For research use only—not for human use. No sales to individuals. Use as intended only.

Batch Information

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Purity:97.01%

Appearance:Liquid

Color:Transparent

Resource Download

COA LCMS HNMR

Product Information

Bioactivity

Description	Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.
Synonyms	NSC-661583, NSC661583, NSC 661583

Chemical Properties

Molecular Weight	302.36
Formula	C₁₅H₂₆O₆
Cas No.	60-01-5
Smiles	CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
Relative Density.	1.032g/mLat 20°C(lit.)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (826.83 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 10 mg/mL (33.07 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3073 mL	16.5366 mL	33.0732 mL	165.3658 mL
5 mM	0.6615 mL	3.3073 mL	6.6146 mL	33.0732 mL
10 mM	0.3307 mL	1.6537 mL	3.3073 mL	16.5366 mL
20 mM	0.1654 mL	0.8268 mL	1.6537 mL	8.2683 mL
50 mM	0.0661 mL	0.3307 mL	0.6615 mL	3.3073 mL
100 mM	0.0331 mL	0.1654 mL	0.3307 mL	1.6537 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Product Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Vitamin DTributyrinprodrugproapoptoticMiaPaca-2InhibitorinhibitGlyceryl tributyratefatty acid triglyceridecell differentiationCaco-2 cellApoptosisantiproliferative21920

Related Tags: Tributyrin chemical structure | Tributyrin formula | Tributyrin molecular weight

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