SARS-CoV-2 (COVID-19) Nucleocapsid protein

Cat# orb638879-1mg

Size : 1mg

Brand : Biorbyt

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SARS-CoV-2 (COVID-19) Nucleocapsid protein

Catalog Number: orb638879

Catalog Numberorb638879
CategoryProteins
DescriptionNucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
ReactivityVirus
TagC-6×His
Form/AppearancePowder
Purity95%
ConjugationUnconjugated
MW47.3 kDa
TargetNucleocapsid protein
Protein SequenceQHO62115.1
SourceSARS-CoV-2 Nucleocapsid protein, His Tag (orb638879) is expressed and secreted by human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1).
Expression SystemHEK293
Expression RegionMet 1 - Ala 419
Endotoxins1.0 EU per μg
NCBIQHO62115.1
Storage-20℃
Buffer/PreservativesPBS, pH7.4
Alternative namesNucleocapsid protein,NP,Protein N
NoteFor research use only
Application notesThis protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.3 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date6 months from date of receipt.
SARS-CoV-2 (COVID-19) Nucleocapsid protein

SDS-PAGE analysis of 2019-nCoV (COVID-19) Nucleocapsid protein