α2C adrenoceptor agonist 1 [928115-79-1]
Referencia T87683-50mg
embalaje : 50mg
Marca : TargetMol
α2C adrenoceptor agonist 1
Copy Product InfoCompound A (α2C adrenoceptor agonist 1) is an orally active, highly selective α2C-adrenoceptor agonist that does not penetrate the central nervous system. It exhibits EC50 and Ki values of 108 nM and 12 nM, respectively. This compound is utilized in research on nasal congestion [1].
Cas No. 928115-79-1
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Compound A (α2C adrenoceptor agonist 1) is an orally active, highly selective α2C-adrenoceptor agonist that does not penetrate the central nervous system. It exhibits EC50 and Ki values of 108 nM and 12 nM, respectively. This compound is utilized in research on nasal congestion [1]. |
| Targets & IC50 | α2C-adrenoceptor:12 nM (Ki), α2C-adrenoceptor:108 nM (EC50) |
| In vivo | Compound A, an α2C adrenoceptor agonist (5 mg/kg; p.o.), exhibits poor brain penetration in Sprague-Dawley rats, with its mean Cmax, Tmax, and area under the curve values being 0.8 μM, 0.7 hours, and 2 μM•h, respectively [1]. |
| Molecular Weight | 315.37 |
| Formula | C16H21N5O2 |
| Cas No. | 928115-79-1 |
| Smiles | C(N1C=2C(=CC=C(N(C(NC)=O)CC)C2)OCC1)C3=CN=CN3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |