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> γ-Lumicolchicine [6901-14-0]

γ-Lumicolchicine [6901-14-0]

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Referencia HY-124479A-1mg

embalaje : 1mg

Marca : MedChemExpress

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Descripciòn

γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569)[1]

Cellular Effect
Cell Line Type Value Description References
MCF7 EC50
1.5 μM
Compound: 4
Cytotoxicity against human MCF7 after 3 days by SRB assay
Cytotoxicity against human MCF7 after 3 days by SRB assay
[PMID: 15730238]
NCI-H460 EC50
2.1 μM
Compound: 4
Cytotoxicity against human H460 after 3 days by SRB assay
Cytotoxicity against human H460 after 3 days by SRB assay
[PMID: 15730238]
SF-268 EC50
3.2 μM
Compound: 4
Cytotoxicity against human SF-268 after 3 days by SRB assay
Cytotoxicity against human SF-268 after 3 days by SRB assay
[PMID: 15730238]
Peso molecular

399.44

Fòrmula

C22H25NO6
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

CC(N[C@@H]1C([C@]2(12)[C@@]3(12)C=C(OC)C2=O)=C3C4=C(OC)C(OC)=C(OC)C=C4CC1)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvente y solubilidad
In Vitro: 

Methanol : 2 mg/mL (5.01 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5035 mL 12.5175 mL 25.0350 mL
5 mM 0.5007 mL 2.5035 mL 5.0070 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias