General Information
| Short Description | Rabbit polyclonal Ccer1 (1-200 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen Region | 1-200 aa |
| Immunogen Sequence | MTQTVNEREDPLNLGGGGWA SSIPLRTWSSYHRRQRGAPV SKRRYRDGPKIEYEASRKQP KQQRSPGSWFQPSRGPYWAL YSNWERCGGPWRPPLIAFQS PLCPAQMIRAYGLHPLCVCC CSCWSGPWNPGWERPPGRKK RWGRRGRGLRRHPRRSFPRN PPIDLSKMLRPVNLSGWRAP GMRAPRNTTQFIMNQVYEDM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Ccer1 (NP_080000.1). |
Additional Info
| Function | Regulator of histone epigenetic modifications and chromatin compaction into the sperm head, required for histone-to-protamine (HTP) transition. HTP is a key event in which somatic histones are first replaced by testis-specific histone variants, then transition proteins (TNPs) are incorporated into the spermatid nucleus, and finally protamines (PRMs) replace the TNPs to promote chromatin condensation. |
| Protein Name | Coiled-Coil Domain-Containing Glutamate-Rich Protein 1 |
| Database Links | |
| Cellular Localisation | NucleusForms Condensates In The Nucleus Through Liquid-Liquid Phase Separation |
| Alternative Antibody Names | Anti-Coiled-Coil Domain-Containing Glutamate-Rich Protein 1 antibodyAnti-CCER1 antibodyAnti-C12orf12 antibody |
Information sourced from Uniprot.org