CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: Psel.KO.2.7]

Specifications

Product Data
Clone Name	Psel.KO.2.7
Applications	FC
Recommended Dilution	Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 106 cells in 100 µl.
Reactivities	Bovine, Equine, Feline, Goat, Human, Mouse, Rat, Sheep
Host	Mouse
Isotype	IgG1
Clonality	Monoclonal
Immunogen	P-selectin transfected 300.19 cells.
Specificity	This antibody recognises the CD62P cell surface antigen, a 140kD glycoprotein also known as P-Selectin.
Formulation	PBS, pH 7.4 Label: PE State: Lyophilized purified IgG fraction from Tissue Culture Supernatant Stabilizer: 1% BSA, 5% Sucrose Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) Absorption emission: 488nm / 575nm
Reconstitution Method	Restore with 1.0 ml distilled water
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	PE
Storage	Store the antibody undiluted Prior to and After reconstitution at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Stability	Shelf life: One year from despatch.
Gene Name	selectin P
Database Link	Entrez Gene 6403 Human UniProt ID P16109
Background	CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster
Synonyms	SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3
Reference Data